Evidence map›Paper›PMID 36003481›Full record

ArticleJTCVS open2022

Prediction of aortic dilatation in surgically repaired type A dissection: A longitudinal study using computational fluid dynamics.

Yu Zhu, Xiao Yun Xu, Ulrich Rosendahl, John Pepper, Saeed Mirsadraee

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in JTCVS open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07623213 (Artificial Intelligence Multimodal Prediction Model-Guided Intensified Follow-up Strategy for 1-Year Outcomes After Surgery for Acute Type A Aortic Dissection), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07623213 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Artificial Intelligence Multimodal Prediction Model-Guided Intensified Follow-up Strategy for 1-Year Outcomes After Surgery for Acute Type A Aortic Dissection: A Multicenter Randomized Controlled Trial

TypeinterventionalSponsorSecond Affiliated Hospital, Zhejiang University, School of MedicineRan2026 to 2029Enrolled1,314ConditionsAcute Type A Aortic Dissection, Stanford Type A Aortic Dissection, Postoperative Aortic Dissection Follow-upArmsUsual Postoperative Follow-up Strategy, AI Prediction Model-Guided Intensified Follow-up Strategy
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yu ZhuDepartment of Chemical Engineering, Imperial College London, London, United Kingdom.
Xiao Yun XuDepartment of Chemical Engineering, Imperial College London, London, United Kingdom.
Ulrich RosendahlNational Heart and Lung Institute, Imperial College London, London, United Kingdom.
John PepperNational Heart and Lung Institute, Imperial College London, London, United Kingdom.
Saeed MirsadraeeNational Heart and Lung Institute, Imperial College London, London, United Kingdom.
Imperial College London · GBHarefield Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To examine the role of a key hemodynamic parameter, namely the true and false lumen pressure difference, to predict progressive aortic dilatation following type A aortic dissection (TAAD) repair. Methods: Four patients with surgically repaired TAAD with multiple follow-up computed tomography angiography scans (4-5 scans per patient; N = 18) were included. Through-plane diameter of the residual native thoracic aorta was measured in various aortic segments during the follow up period (mean follow-up: 49.6 ± 31.2 months). Computational flow analysis was performed to estimate true and false lumen pressure difference at the same locations and the correlation with aortic size change was studied using a linear mixed effects model. Results: Greater pressure difference between the true and false lumen was consistent with greater aortic diameter expansion during the follow up period (linear mixed effects analysis; coefficient, 0.26; 95% confidence interval, 0.15-0.37; Conclusions: Computational fluid dynamic assessment of standard aortic computed tomography angiography offers a noninvasive technique that predicts the risk of aortic dilatation following TAAD. The technique may be used to plan closer observation or intervention in high-risk patients.

Indexed as

aortic dilatationCFD, computational fluid dynamicscomputational fluid dynamicsCTA, computed tomography angiographyCT, computed tomographyFL, false lumenluminal pressure differenceROC, receiver operating characteristicTAAD, type A aortic dissectionTBAD, type B aortic dissectionTL, true lumentype A aortic dissection

Identifiers

PMID36003481
PMCPMC9390758
OpenAlexW4210906121

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.