Evidence map›Paper›PMID 36003469›Full record

ArticleJTCVS open2022

Impact of preoperative versus postoperative dialysis on left ventricular assist device outcomes: An analysis from the Society of Thoracic Surgeons Interagency Registry for Mechanically Assisted Circulatory Support database.

J Hunter Mehaffey, Ryan Cantor, Susan Myers, Nicholas R Teman, John A Kern, Gorav Ailawadi, Francis Pagani, James Kirklin, Kenan Yount, Leora Yarboro

Open access · goldAbstract read
In one paragraph

Article in JTCVS open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

J Hunter MehaffeyDivision of Thoracic and Cardiovascular Surgery, University of Virginia, Charlottesville, Va.
Ryan CantorKirklin Institute for Research in Surgical Outcomes, University of Alabama, Birmingham, Ala.
Susan MyersKirklin Institute for Research in Surgical Outcomes, University of Alabama, Birmingham, Ala.
Nicholas R TemanDivision of Thoracic and Cardiovascular Surgery, University of Virginia, Charlottesville, Va.
John A KernDivision of Thoracic and Cardiovascular Surgery, University of Virginia, Charlottesville, Va.
Gorav AilawadiDivision of Thoracic and Cardiovascular Surgery, University of Virginia, Charlottesville, Va.
Francis PaganiDepartment of Cardiothoracic Surgery, University of Michigan, Ann Arbor, Mich.
James KirklinKirklin Institute for Research in Surgical Outcomes, University of Alabama, Birmingham, Ala.
Kenan YountDivision of Thoracic and Cardiovascular Surgery, University of Virginia, Charlottesville, Va.
Leora YarboroDivision of Thoracic and Cardiovascular Surgery, University of Virginia, Charlottesville, Va.
University of Virginia · USUniversity of Alabama · USKirklin Clinic · USUniversity of Michigan–Ann Arbor · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Chronic kidney disease and renal failure are common in patients being considered for left ventricular assist device support. We sought to evaluate the outcomes of patients undergoing left ventricular assist device implantation with preoperative dialysis and those with new-onset postoperative renal failure requiring dialysis. Methods: All patients (n = 14,090) undergoing primary left ventricular assist device implantation who were listed in the Interagency Registry for Mechanically Assisted Circulatory Support database (2014-2019) were evaluated. Landmark analysis then stratified patients alive at 1 month by preoperative dialysis and at 1 month postoperatively, preoperative dialysis only, postoperative dialysis only, and no dialysis. Results: Of 14,090 patients undergoing left ventricular assist device implantation, patients on dialysis (400%, 3%) preoperatively had significantly higher mortality at 1 month (18% vs 6%, Conclusions: Preoperative renal failure is associated with 3 times higher mortality and worse morbidity in patients receiving a left ventricular assist device. However, one-third of patients with preoperative dialysis will recover renal function postimplant with similar long-term survival and quality of life as those without dialysis.

Indexed as

BIVAD, biventricular assist deviceCI, confidence intervaldialysisESRD, end-stage renal diseaseINTERMACSINTERMACS, interagency registry for mechanically assisted circulatory supportLVADLVAD, left ventricular assist deviceOR, odds ratiooutcomesrenal failureSTS, Society of Thoracic Surgeons

Identifiers

PMID36003469
PMCPMC9390495
OpenAlexW4206896944

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.