Evidence map›Paper›PMID 36003325›Full record

ArticleBrain communications2022

Altered high-energy phosphate and membrane metabolism in Pelizaeus-Merzbacher disease using phosphorus magnetic resonance spectroscopy.

Jeremy J Laukka, Kevin M Kain, Anirudha S Rathnam, Jasloveleen Sohi, Dalal Khatib, John Kamholz, Jeffrey A Stanley

Open access · goldAbstract read
In one paragraph

Article in Brain communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Skeletal MuscleDiagnostics (Basel, Switzerland) · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Jeremy J LaukkaDepartment of Medical Education, University of Toledo College of Medicine and Life Sciences, Toledo, OH, USA.
Kevin M KainCollege of Osteopathic Medicine, Kansas City University, Kansas City, MO, USA.
Anirudha S RathnamDepartment of Neurology, Henry Ford Health System, Detroit, MI, USA.
Jasloveleen SohiDepartment of Neurology, Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, MI, USA.
Dalal KhatibDepartment of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI, USA.
John KamholzDepartment of Neurology, Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, MI, USA.
Jeffrey A StanleyDepartment of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI, USA.ORCID https://orcid.org/0000-0003-2355-480X
Wayne State University · USHenry Ford Health System · USKansas City University · USUniversity of Iowa · USUniversity of Toledo Medical Center · US

Funding

In Vivo 31P Spectroscopy and MRI in ADHDR01MH065420 · NIMH · WAYNE STATE UNIVERSITY · PI STANLEY, JEFFREY A · 2003 to 2014
$3.3M
NIMH NIH HHS R01 MH065420
6 · The paper itself

Abstract

Pelizaeus-Merzbacher disease is an X-linked recessive leucodystrophy of the central nervous system caused by mutations affecting the major myelin protein, proteolipid protein 1. The extent of the altered

Indexed as

biochemistryhigh-energy phosphatemembrane phospholipidsPelizaeus–Merzbacher diseasephosphorus magnetic resonance spectroscopy

Identifiers

PMID36003325
PMCPMC9396944
OpenAlexW4290080660

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.