Evidence map›Paper›PMID 36002959›Full record

ArticleNeuroImage. Clinical2022

Surface-based abnormalities of the executive frontostriatial circuit in pediatric TBI.

Kaitlyn M Greer, Aubretia Snyder, Chase Junge, Madeleine Reading, Sierra Jarvis, Chad Squires, Erin D Bigler, Karteek Popuri, Mirza Faisal Beg, H Gerry Taylor and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NeuroImage. Clinical, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 2 countries.

Kaitlyn M GreerDepartment of Psychology, Brigham Young University, Provo, UT, United States.
Aubretia SnyderDepartment of Psychology, Brigham Young University, Provo, UT, United States.
Chase JungeNeuroscience Center, Brigham Young University, Provo, UT, United States.
Madeleine ReadingDepartment of Psychology, Brigham Young University, Provo, UT, United States.
Sierra JarvisDepartment of Psychology, Brigham Young University, Provo, UT, United States.
Chad SquiresDepartment of Psychology, Brigham Young University, Provo, UT, United States.
Erin D BiglerDepartment of Psychology, Brigham Young University, Provo, UT, United States; Neuroscience Center, Brigham Young University, Provo, UT, United States.
Karteek PopuriDepartment of Computer Science, Memorial University Newfoundland, St. John's, Newfoundland, Canada.
Mirza Faisal BegSchool of Engineering Science, Simon Fraser University, Burnaby, B.C., Canada.
H Gerry TaylorAbigail Wexner Research Institute at Nationwide Children's Hospital Research Institute, Columbus, OH, United States; Department of Pediatrics, The Ohio State University, Columbus, OH, United States.
Kathryn VannattaAbigail Wexner Research Institute at Nationwide Children's Hospital Research Institute, Columbus, OH, United States; Department of Pediatrics, The Ohio State University, Columbus, OH, United States.
Cynthia A GerhardtAbigail Wexner Research Institute at Nationwide Children's Hospital Research Institute, Columbus, OH, United States; Department of Pediatrics, The Ohio State University, Columbus, OH, United States.
Kenneth RubinDepartment of Human Development and Quantitative Methodology, University of Maryland, College Park, MD, United States.
Keith Owen YeatesDepartment of Psychology, University of Calgary, Calgary, Alberta, Canada; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada; Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada.
Derin CobiaDepartment of Psychology, Brigham Young University, Provo, UT, United States; Neuroscience Center, Brigham Young University, Provo, UT, United States. Electronic address: derin_cobia@byu.edu.
Brigham Young University · USNationwide Children's Hospital · USMemorial University of Newfoundland · CASimon Fraser University · CAUniversity of Calgary · CAUniversity of Maryland, College Park · US

Funding

Predicting Outcomes in Children with Mild Traumatic Brain InjuryR01HD076885 · NICHD · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI YEATES, KEITH O · 2013 to 2018
$3.0M
NICHD NIH HHS R01 HD076885
6 · The paper itself

Abstract

Childhood traumatic brain injury (TBI) is one of the most common causes of acquired disability and has significant implications for executive functions (EF), such as impaired attention, planning, and initiation that are predictive of everyday functioning. Evidence has suggested attentional features of executive functioning require behavioral flexibility that is dependent on frontostriatial circuitry. The purpose of this study was to evaluate surface-based deformation of a specific frontostriatial circuit in pediatric TBI and its role in EF. Regions of interest included: the dorsolateral prefrontal cortex (DLPFC), caudate nucleus, globus pallidus, and the mediodorsal nucleus of the thalamus (MD). T1-weighted magnetic resonance images were obtained in a sample of children ages 8-13 with complicated mild, moderate, or severe TBI (n = 32) and a group of comparison children with orthopedic injury (OI; n = 30). Brain regions were characterized using high-dimensional surface-based brain mapping procedures. Aspects of EF were assessed using select subtests from the Test of Everyday Attention for Children (TEA-Ch). General linear models tested group and hemisphere differences in DLPFC cortical thickness and subcortical shape of deep-brain regions; Pearson correlations tested relationships with EF. Main effects for group were found in both cortical thickness of the DLPFC (F

Indexed as

Brain Injuries, TraumaticAdolescentAttentionChildCognitionExecutive FunctionHumansNeuropsychological TestsCaudateChildrenHead injuryNeuroimagingShape analysis

Identifiers

PMID36002959
PMCPMC9421496
OpenAlexW4288737564

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.