Evidence map›Paper›PMID 36002823›Full record

Observational studyBMC psychiatry2022

Chronic pain, mental health and functional impairment in adult refugees from Syria resettled in Norway: a cross-sectional study.

Alexander Nissen, Kamila Angelika Hynek, David Scales, Per Kristian Hilden, Melanie Straiton

Registry-linked trialOpen access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03742128 (The REFUGE-study), which is not on this map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03742128 unknown statusnot on this map

The REFUGE-study: Health and Quality of Life Among Resettled Syrian Refugees and Asylum-seekers in Norway (REFUGE-I)

TypeobservationalSponsorNorwegian Center for Violence and Traumatic Stress StudiesRan2018 to 2019Enrolled3,000ConditionsMental Health Impairment, Stress, Psychological, Quality of Life, Health, Subjective
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 30 citations in OpenAlex.

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  7. International journal of environmental research and public health · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Alexander NissenSection for Trauma, Catastrophes and Forced Migration - Adults and Elderly, Norwegian Centre for Violence and Traumatic Stress Studies, 0484, Oslo, Norway. a.f.w.nissen@nkvts.no.
Kamila Angelika HynekDivision for Mental and Physical Health, Norwegian Institute of Public Health, Skøyen, PO Box 222, 0213, Oslo, Norway.
David ScalesSection of Hospital Medicine, Division of General Internal Medicine, Department of Internal Medicine, Weill Cornell Medicine, 525 E 68th Street, Box 331, New York, NY, 10065, USA.
Per Kristian HildenSection for Trauma, Catastrophes and Forced Migration - Adults and Elderly, Norwegian Centre for Violence and Traumatic Stress Studies, 0484, Oslo, Norway.
Melanie StraitonDivision for Mental and Physical Health, Norwegian Institute of Public Health, Skøyen, PO Box 222, 0213, Oslo, Norway.
Norwegian Centre for Violence and Traumatic Stress Studies · NONorwegian Institute of Public Health · NOCornell University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLimited research exists on pain and especially the co-occurrence of pain and mental ill health in general refugee populations. The present study aimed to approximate the prevalence of chronic pain (CP) among adult refugees from Syria resettled in Norway; investigate the association between CP and mental ill health; and explore how CP and mental ill health associate with both perceived general health and functional impairment. Gender as potential effect modifier in these associations was also examined.

methodsCross-sectional, postal survey questionnaire. INCLUSION CRITERIA: ≥ 18 years old; refugee from Syria; and arrived in Norway between 2015 and 2017. Study sample was randomly drawn from full population registries, and n = 902 participated (participation rate ≈10%). CP was measured with 10 items on pain lasting for ≥ 3 consecutive months last year. Symptoms of anxiety, depression and PTSD were measured with the HSCL and HTQ scales, respectively. Ordered and binomial logistic regressions were used in analyses. Gender was tested as effect modifier with Wald test for interaction.

resultsIn the sample overall, the proportion of participants who reported severe CP was 43.1%. There was strong evidence that anxiety, depression and PTSD were associated with higher levels of CP. In fully adjusted regression models, including both CP and mental health variables, CP was strongly associated with poor perceived general health whereas mental health showed much weaker associations. The association between mental health (anxiety and PTSD) and functional impairment was highly gender specific, with strong associations in men but not in women. CP was strongly associated with functional impairment with no difference across gender.

conclusionThe study shows a high burden of CP in a general population of adult refugees from Syria with likely substantial adverse consequences for daily functioning. The strong association between CP and mental ill health suggests personnel working with refugees' health should be attuned to their co-occurrence as both problems may need to be addressed for either to be effectively mitigated. A clear mismatch exists between the burden on health caused by pain in general refugee populations and the amount of available evidence to guide mitigating strategies.

trial registrationNCT03742128.

Indexed as

Chronic PainRefugeesStress Disorders, Post-TraumaticAdolescentAdultCross-Sectional StudiesDepressionFemaleHumansMaleMental HealthSyriaAnxietyDepressionFunctional impairmentMental healthPainPTSDRefugeesSyria

Identifiers

PMID36002823
PMCPMC9404590
OpenAlexW4292995086

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.