Evidence map›Paper›PMID 36002808›Full record

ArticleBMC geriatrics2022

Associations between sarcopenia with asthmatic prevalence, lung function and comorbidity.

Zhigang Hu, Yufeng Tian, Xinyu Song, Fanjun Zeng, Ailan Yang

Open access · goldAbstract read
In one paragraph

Article in BMC geriatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. How Pragmatic Are Sarcopenia Intervention Studies? A Systematic Review.Journal of cachexia, sarcopenia and muscle · 2026
    Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Zhigang HuDepartment of Respiratory and Critical Care Medicine, The First College of Clinical Medicine Science, China Three Gorges University, Yichang, 443003, People's Republic of China. hxq910813@163.com.
Yufeng TianDepartment of Academic Management, Clinical Research Center, China Three Gorges University, NO. 183 Yiling Road, Yichang, 443003, People's Republic of China.
Xinyu SongDepartment of Respiratory and Critical Care Medicine, The First College of Clinical Medicine Science, China Three Gorges University, Yichang, 443003, People's Republic of China. sxy1421@163.com.
Fanjun ZengDepartment of Respiratory and Critical Care Medicine, The First College of Clinical Medicine Science, China Three Gorges University, Yichang, 443003, People's Republic of China.
Ailan YangDepartment of Respiratory and Critical Care Medicine, Yichang Central People's Hospital at Zhijiang, NO. 183 Yiling Road, Zhijiang, 443003, People's Republic of China.
China Three Gorges University · CNYichang Central People's Hospital · CN

Funding

China Health and Retirement Longitudinal StudyR01AG037031 · NIA · PEKING UNIVERSITY · PI STRAUSS, JOHN A, WANG, YAFENG · 2010 to 2024
$15.1M
Towards improving the measurement of health and disability trends, the compressioR01AG034479 · NIA · WORLD HEALTH ORGANIZATION · PI CHATTERJI, SOMNATH · 2010 to 2014
$5.3M
Bringing positive and negative events to mind: Effects of age on emotional memory retrievalR01AG075031 · NIA · BOSTON COLLEGE · PI Elizabeth Ann Kensinger · 2022 to 2026
$2.0M
China Health and Retirement Longitudinal Study - PilotR21AG031372 · NIA · PEKING UNIVERSITY · PI ZHAO, YAOHUI · 2007 to 2008
$273k
Harmonizing health outcomes and determinants across longitudinal studies on agingR21AG034263 · NIA · WORLD HEALTH ORGANIZATION · PI CHATTERJI, SOMNATH, KOWAL, PAUL R. · 2011 to 2012
$255k
NIA NIH HHS R01 AG034479NIA NIH HHS R01 AG037031NIA NIH HHS R01 AG075031NIA NIH HHS R21 AG031372NIA NIH HHS R21 AG034263
6 · The paper itself

Abstract

backgroundSarcopenia is listed as a treatment trait in behavioral/risk factors for severe asthma, but studies on asthma and sarcopenia are lacking. This study aimed to determine the associations between sarcopenia with asthmatic prevalence, symptoms, lung function and comorbidities.

methodsFifteen thousand four hundred four individuals from the China Health and Retirement Longitudinal Study(CHARLS) and 10,263 individuals from the Study on global AGEing and adult health(SAGE) in China were included in this study. Four components of this study were used to assess the bidirectional association in the prevalence between sarcopenia with asthma, and estimate the relationships between sarcopenia with asthmatic symptoms, lung function and comorbidities via generalized additive models. The 10-item Center for Epidemiological Studies-Depression Scale ≥ 12 scores was classified as depression.

resultsIn the CHARLS and SAGE, the prevalence of sarcopenia in asthmatics was higher than those without asthma. Asthmatics with sarcopenia had a significantly increased prevalence of severe shortness of breath(sarcopenia yes vs. no, adjusted OR = 3.71, 95%CI: 1.43-9.60) and airway obstruction in the SAGE(sarcopenia yes vs. no, adjusted OR = 6.82, 95%CI: 2.54-18.34) and an obvious reduction of PEF in the CHARLS and SAGE(sarcopenia yes vs. no, adjusted RR = 0.86, 95%CI: 0.82-0.91) compared to asthmatics without sarcopenia. The presence of sarcopenia was positively associated with the prevalence of chronic obstructive pulmonary disease(sarcopenia yes vs no, adjusted OR = 5.76, 95%CI:2.01-16.5) and depression(sarcopenia yes vs no, adjusted OR = 1.87, 95%CI:1.11-3.14) in asthmatics.

conclusionsOur findings indicated that sarcopenia partakes in the development of asthma by affecting lung function and comorbidities and maybe considered a treatable trait of asthma management.

Indexed as

AsthmaSarcopeniaComorbidityHumansLongitudinal StudiesLungPrevalenceAsthmaComorbidityLung functionPrevalenceSarcopenia

Identifiers

PMID36002808
PMCPMC9404581
OpenAlexW4293004803

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.