ReviewEuropean review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity2022
The effects of interventions to enhance cognitive and physical functions in older people with cognitive frailty: a systematic review and meta-analysis.
Review in European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Music-with-Movement (Simultaneous Cognitive-motor Dual-task Training) on Cognitive and Physical Performance of People With Potentially Reversible Cognitive Frailty: a Randomised Controlled Trial
Comparison of the Effectiveness of Dual-Task Training and Computer-Based Cognitive Rehabilitation in Older Adults With Mild Cognitive Impairment
Who cites it
20 citing papers in PubMed.
- Trial
- Effects of Virtual Reality Motor-Cognitive Training for Older People With Cognitive Frailty: Multicentered Randomized Controlled Trial.Journal of medical Internet research · 2024Trial
- Multidimensional Frailty and Resilience in Relation to Quality of Life in Senior Patients with Cardiovascular Disease: An Exploratory Cross-Sectional Pilot Study.Journal of clinical medicine · 2026Article
- Multiuser Exercise-Based Telerehabilitation Intervention for Older Adults with Frailty: A Pilot Study.NeuroSci · 2026Article
- Remote Monitoring of Instrumental Activities of Daily Living Reveals Intrinsic Capacity in Older Adults.Gerontology · 2026Article
- A nomogram model for identifying cognitive frailty in elderly patients with chronic diseases: a multicenter cross-sectional study.Frontiers in public health · 2026Observational
- Article
- Association between coexisting physical, cognitive, and social frailty and sarcopenia in patients undergoing maintenance hemodialysis.Frontiers in medicine · 2025Article
- A 20-s Video-Based Assessment of Cognitive Frailty: Results from a Cohort Study within the Precision Aging Network.Gerontology · 2025Article
- Interventions for cognitive frailty: developing a Delphi consensus with multidisciplinary and multisectoral experts.Frontiers in aging neuroscience · 2025Article
- The Effect of the Mediterranean Diet-Integrated Gamified Home-Based Cognitive-Nutritional (GAHOCON) Training Programme for Older People With Cognitive Frailty: Pilot Randomized Controlled Trial.JMIR rehabilitation and assistive technologies · 2024Article
- The Impact of Frailty on Patients With AF and HFrEF Undergoing Catheter Ablation: A Nationwide Population Study.JACC. Advances · 2024Article
- Reduced Anxiety and Depression and Improved Mood in Older Adults Living in Care Homes After Participating in Chair Yoga.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2024Article
- Construction and verification of a risk prediction model for cognitive frailty in older patients with chronic obstructive pulmonary disease and diabetes mellitus.The Journal of international medical research · 2024Article
- The mitochondrial function of peripheral blood cells in cognitive frailty patients.Frontiers in aging neuroscience · 2024Article
- Impact of Exercise Interventions on Sustained Brain Health Outcomes in Frail Older Individuals: A Comprehensive Review of Systematic Reviews.Healthcare (Basel, Switzerland) · 2023Review
- Enhancing Visual Exploration through Augmented Gaze: High Acceptance of Immersive Virtual Biking by Oldest Olds.International journal of environmental research and public health · 2023Article
- Myokines as mediators of exercise-induced cognitive changes in older adults: protocol for a comprehensive living systematic review and meta-analysis.Frontiers in aging neuroscience · 2023Article
- A review of frailty instruments in human medicine and proposal of a frailty instrument for dogs.Frontiers in veterinary science · 2023Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionCognitive frailty is the co-existence of mild cognitive impairment and physical frailty that increases the risk of adverse health outcomes. The existing systematic reviews on cognitive frailty in the literature have focused only on identifying associated factors and adverse outcomes, and their relationship with frailty and cognition. This study aimed to examine the effects of interventions on cognitive functions, frailty, and physical functions and provide an overview of intervention components used in older people with cognitive frailty.
methodsThis is a systematic review and meta-analysis. Medline, PubMed, CINAHL, Embase, PsycINFO, and Cochrane were searched for publishing during 2013-2021. Studies were selected based on the following eligibility criteria: 1) older people (age ≥ 60 years), 2) cognitive frailty, 3) outcomes on frailty or cognition or physical function, and 4) randomized controlled trial with any type of intervention. The Physiotherapy Evidence Database (PEDro) scale was used to rate the quality of the included studies. The review protocol was registered with PROSPERO (CRD42021251321).
resultsTwo thousand five hundred six studies were identified, 9 were eligible, and 8 were included in the meta-analysis. The standardized mean difference (Hedges G) between groups of cognitive functions was 0.95, frailty status was 0, physical function in walking was -1.67, and the physical function in core strength assessment was 3.39. Physical activity appeared as an essential component in all interventions for older people with cognitive frailty. DISCUSSION: All interventions include physical activity as one of the components. Other components include cognitive training, nutrition education, behavioural intervention, mind-body intervention, psychosocial support, and virtual reality. The interventions are effective to promote cognitive and physical functions, but not physical frailty.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.