Evidence map›Paper›PMID 36002686›Full record

ArticleSurgical endoscopy2023

Increased incidence of marginal ulceration following conversion of sleeve gastrectomy to Roux-en-Y gastric bypass: a multi-institutional experience.

Brigitte Anderson, Tingting Zhan, Luke Swaszek, Caroline Sanicola, Neil King, Aurora Pryor, Konstantinos Spaniolas, Renee Tholey, Francesco Palazzo, Alec Beekley and 1 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Surgical endoscopy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Review
  4. Sex- and operation-dependent effects on 5-year weight loss results of bariatric surgery.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2024
    Observational
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Brigitte AndersonDepartment of Surgery, Thomas Jefferson University, Philadelphia, PA, USA.
Tingting ZhanDepartment of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, Philadelphia, PA, USA.
Luke SwaszekDepartment of Surgery, Temple University Hospital, Philadelphia, PA, USA.
Caroline SanicolaDepartment of Surgery, Stony Brook Medicine, Stony Brook, NY, USA.
Neil KingDepartment of Surgery, Temple University Hospital, Philadelphia, PA, USA.
Aurora PryorDepartment of Surgery, Stony Brook Medicine, Stony Brook, NY, USA.
Konstantinos SpaniolasDepartment of Surgery, Stony Brook Medicine, Stony Brook, NY, USA.
Renee TholeyDepartment of Surgery, Thomas Jefferson University, Philadelphia, PA, USA.
Francesco PalazzoDepartment of Surgery, Thomas Jefferson University, Philadelphia, PA, USA.
Alec BeekleyDepartment of Surgery, Thomas Jefferson University, Philadelphia, PA, USA.
Talar TatarianDepartment of Surgery, Thomas Jefferson University, Philadelphia, PA, USA. talar.tatarian@jefferson.edu.ORCID 0000-0002-0845-3659
Thomas Jefferson University · USStony Brook Medicine · USTemple University Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMarginal ulcer (MU) formation is a serious complication following Roux-en-Y Gastric Bypass (RYGB). Incidental data suggested a higher incidence of MU following conversion of Sleeve Gastrectomy to RYGB (S-RYGB). Herein, we evaluate the incidence of MU after primary versus secondary RYGB.

methodsAfter IRB approval, each institution's electronic medical record and MBSAQIP database were queried to retrospectively identify adult patients who underwent primary RYGB (P-RYGB), Gastric Banding to RYGB (B-RYGB), or S-RYGB between 2014 and 2019, with minimum 1 year follow-up. Patient demographics, operative data, and post-operative outcomes were compared. Numeric variables were compared via two-sample t test, Wilcoxon test or Kruskal Wallis rank sum test. Two-sample proportion test or Fisher's exact test was employed for categorical and binary variables. p < 0.05 marked statistical significance.

results748 patients underwent RYGB: P-RYGB n = 584 [78.1%]; B-RYGB n = 98 [13.1%]; S-RYGB n = 66 [8.8%]. Most patients were female (83.2%). Mean age was 45.7 years. Forty-six (n = 6.1%) patients developed MU, a median of 14 ± 32.2 months (range 0.5-82) post-operatively. Incidence of MU was significantly higher for patients undergoing S-RYGB (n = 9 [13.6%]), compared to P-RYGB (n = 34 [5.8%]) and B-RYGB (n = 3 [3.1%]) (p = 0.023). Median time (months) to MU was significantly shorter for patients who underwent S-RYGB (5 ± 6) compared to P-RYGB or B-RYGB (19 ± 37.5) (p = 0.035). Among those who developed MU, there was no significant difference in H. pylori status, NSAID, steroid, or tobacco use, irrespective of operation performed.

conclusionIn this multi-institutional cohort, patients who underwent S-RYGB had a significantly higher incidence of MU than those with P-RYGB or B-RYGB. Further research is needed to elucidate its pathophysiology and prevention strategies.

Indexed as

Gastric BypassObesity, MorbidPeptic UlcerAdultFemaleGastrectomyHumansIncidenceMaleMiddle AgedRetrospective StudiesBariatric surgeryGastric bypassMarginal ulcer

Identifiers

PMID36002686
OpenAlexW4293102343

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.