ArticleNature2022
Brain-phenotype models fail for individuals who defy sample stereotypes.
Abstract read
In one paragraph
Article in Nature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 109 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
109citing papers in PubMed, 2 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
109 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Structural Brain Differences in the Alzheimer's Disease Continuum: Insights Into the Heterogeneity From a Large Multisite Neuroimaging Consortium.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025Pooled it
- Machine Learning and Prediction in Fetal, Infant, and Toddler Neuroimaging: A Review and Primer.Biological psychiatry · 2023Pooled it
- Trial
- Stratification of responses to tDCS intervention in a healthy pediatric population based on resting-state EEG profiles.Scientific reports · 2023Trial
- Mesocorticolimbic Dopamine-Reward Tract Alterations and the 'Dark Side' of Methamphetamine Addiction.Addiction biology · 2026Article
- Feature selection leads to divergent neurobiological interpretations of brain-based machine learning biomarkers.Nature human behaviour · 2026Article
- Linking the exposome to the brain-behaviour phenotype.Nature reviews. Neuroscience · 2026Review
- Racialized Heteroscedasticity in Neuroimaging Features, Behavior Measures, and Neuroimaging-Based Predictive Models.Research square · 2026Article
- Regional, functional and transcriptomic decoding of multidimensional brain structure alterations in obsessive-compulsive disorder.Nature communications · 2026Article
- Feature overlap in transdiagnostic connectome-based models of sustained attention and autism symptoms.medRxiv : the preprint server for health sciences · 2026Article
- Using connectome-based predictive models to reveal the systems standardized tests and clinical symptoms are reflecting.Nature communications · 2026Article
- Feasibility of Precision Functional Mapping in Youth Multi-Echo fMRI Data.bioRxiv : the preprint server for biology · 2026Article
- The role of age in the relationship between brain structure and cognition: moderator or confound?Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- The landscape of dementia research, diagnosis, treatment, and care in Latin America.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Review
- Socioeconomic Status Is Associated With Reward Processing, Interleukin 1β, Striatal Connectivity, and Antidepressant Outcomes in Individuals With Major Depressive Disorder: A CAN-BIND-1 Report.Biological psychiatry global open science · 2026Article
- Optimizing functional connectivity scanning conditions for predicting autistic traits.medRxiv : the preprint server for health sciences · 2026Article
- Impulsivity and neuroticism share distinct functional connectivity signatures with alcohol-use risk in youth.Molecular psychiatry · 2026Article
- Representing Brain-Behavior Associations by Retaining High-Motion Minoritized Youth.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026Article
- Digital Mental Health Through an Intersectional Lens: A Narrative Review.Healthcare (Basel, Switzerland) · 2026Review
- Individual identifiability following Procrustes alignment of functional gradients: effect of subspace dimensionality.Communications biology · 2026Article
49 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Abigail S GreeneInterdepartmental Neuroscience Program, Yale School of Medicine, New Haven, CT, USA. abigail.greene@yale.edu.ORCID http://orcid.org/0000-0001-6011-7903
Xilin ShenDepatment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA.
Stephanie NobleDepatment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA.ORCID http://orcid.org/0000-0002-4804-5553
Corey HorienInterdepartmental Neuroscience Program, Yale School of Medicine, New Haven, CT, USA.ORCID http://orcid.org/0000-0001-6738-1029
C Alice HahnDepatment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA.
Jagriti AroraDepatment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA.
Fuyuze TokogluDepatment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA.
Marisa N SpannDepartment of Psychiatry, Columbia University Irving Medical Center, New York, NY, USA.
Carmen I CarriónDepartment of Neurology, Yale School of Medicine, New Haven, CT, USA.ORCID http://orcid.org/0000-0002-7981-9793
Daniel S BarronDepartment of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-0686-6337
Gerard SanacoraDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, USA.
Vinod H SrihariDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, USA.ORCID http://orcid.org/0000-0003-1556-2332
Scott W WoodsDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, USA.
Dustin ScheinostInterdepartmental Neuroscience Program, Yale School of Medicine, New Haven, CT, USA.ORCID http://orcid.org/0000-0002-6301-1167
R Todd ConstableInterdepartmental Neuroscience Program, Yale School of Medicine, New Haven, CT, USA. todd.constable@yale.edu.ORCID http://orcid.org/0000-0001-5661-9521
Funding
Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9MMEDICAL SCIENTIST TRAINING PROGRAMT32GM007205 · NIGMS · YALE UNIVERSITY · PI KAZMIERCZAK, BARBARA I · 1985 to 2019
$42.9MMapping the Human Connectome: Structure, Function, and HeritabilityU54MH091657 · NIMH · WASHINGTON UNIVERSITY · PI UGURBIL, KAMIL, VAN ESSEN, DAVID C · 2010 to 2014
$34.7MYale Alzheimer Disease Research CenterP30AG066508 · NIA · YALE UNIVERSITY · PI STEPHEN M STRITTMATTER, CHRISTOPHER H VAN DYCK · 2020 to 2026
$30.2MNRSA Training CoreTL1TR001864 · NCATS · YALE UNIVERSITY · PI CANTLEY, LLOYD G, EDELMAN, E. JENNIFER · 2016 to 2025
$9.9MClinical Neuroscience Research Training Program in PsychiatryT32MH019961 · NIMH · YALE UNIVERSITY · PI Christopher John Pittenger · 1996 to 2026
$5.9MAn Individualized, Multidimensional Dimensional Approach to PsychopathologyR01MH121095 · NIMH · YALE UNIVERSITY · PI CONSTABLE, R TODD, SCHEINOST, DUSTIN · 2019 to 2023
$4.2MSTEP-ED:Reducing Duration of Untreated Psychosis and its Impact in the U.S.R01MH103831 · NIMH · YALE UNIVERSITY · PI SRIHARI, VINOD H. · 2013 to 2017
$3.9MNCATS NIH HHS TL1 TR001864NCATS NIH HHS UL1 TR001863NIA NIH HHS P30 AG066508NIGMS NIH HHS T32 GM007205NIMH NIH HHS R01 MH103831NIMH NIH HHS R01 MH121095NIMH NIH HHS T32 MH019961NIMH NIH HHS U54 MH091657
Abstract
Individual differences in brain functional organization track a range of traits, symptoms and behaviours
Indexed as
BrainComputer SimulationIndividualityPhenotypeStereotypingDatasets as TopicHumansMental Status and Dementia TestsModels, Biological
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.