ArticleJournal of atherosclerosis and thrombosis2023
Clinical Outcomes and Unique Restenosis of Calcified Nodule in Heavily Calcified Coronary Artery.
Article in Journal of atherosclerosis and thrombosis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed.
- Calcified nodule as a distinct morphological risk factor after intravascular ultrasound-guided percutaneous coronary intervention.Heart and vessels · 2026Article
- Practical Management in Coronary In-Stent Restenosis: A Narrative Review.Journal of clinical medicine · 2026Review
- Ostial right coronary artery lesions: what to know and how to overcome.Cardiovascular intervention and therapeutics · 2026Review
- Clinical expert consensus document on rotational atherectomy from the Japanese association of cardiovascular intervention and therapeutics: update 2026.Cardiovascular intervention and therapeutics · 2026Review
- 3-Dimensional Wiring Allows for ARCADIA Technique Followed by Rotational Atherectomy for Calcified Nodules.JACC. Case reports · 2025Article
- Intra-Calcium Modification: New Promise for Calcified Nodule in Percutaneous Coronary Intervention?JACC. Case reports · 2025Article
- Plaque rupture and calcified nodules: major contributors to out-of-hospital cardiac arrest in acute myocardial infarction.Cardiovascular intervention and therapeutics · 2025Article
- Analysis of the impact of nodular calcification on clinical outcome after drug-coated balloon angioplasty for femoropopliteal lesions.CVIR endovascular · 2025Article
- An effective treatment for repeated coronary in-stent restenosis using rotational atherectomy after aggressive wire penetration through the calcified nodule: a case report.European heart journal. Case reports · 2025Article
- Impact of Angiotensin-Converting Enzyme Inhibitor on Coronary Artery Calcification Evaluated by Intravascular Ultrasound: A Retrospective Cohort Study.Health science reports · 2025Article
- Clinical outcomes of percutaneous coronary intervention for severely calcified lesions: comparison between the morphologies of severely calcified coronary lesions.Heart and vessels · 2025Article
- Deep dive into intravascular coronary imaging in calcified lesions.Cardiovascular intervention and therapeutics · 2025Review
- Current Role of Excimer Laser Coronary Angioplasty Atherectomy in Calcified Coronary Artery Disease Management.JACC. Case reports · 2025Article
- Right Coronary Artery Calcified Nodule Pre-TAVI Treatment Facilitated by ELCA Atherectomy.JACC. Case reports · 2025Article
- Optical coherence tomography findings after drug-coated balloon treatment forFrontiers in cardiovascular medicine · 2025Article
- Vascular response following implantation of the third-generation drug-eluting resorbable coronary magnesium scaffold: an intravascular imaging analysis of the BIOMAG-I first-in-human study.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2024Article
- Distinct Challenges of Eruptive and Non-Eruptive Calcified Nodules in Percutaneous Coronary Intervention.Current cardiology reports · 2024Review
- Coronary calcifications, the Achilles heel in coronary interventions.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2024Review
- Lifetime management of severely calcified coronary lesions: the treatment algorithm focused on the shape of calcification.Cardiovascular intervention and therapeutics · 2023Review
- Rotational atherectomy to left circumflex ostial lesions: tips and tricks.Cardiovascular intervention and therapeutics · 2023Review
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsCalcified nodule (CN) has been known as the advanced stage of coronary calcification. However, clinical outcomes following percutaneous coronary intervention (PCI) to CN remain unknown. This study aimed to compare clinical outcomes, including target lesion revascularization (TLR), between calcified coronary lesions with and without CN.
methodsTwo hundred forty-nine lesions undergoing intravascular ultrasound-guided PCI with rotational atherectomy (RA) were enrolled and divided into the CN group (n=100) and the non-CN group (n=149) according to the presence of CN. The cumulative incidence of clinically driven TLR (CD-TLR) and the reasons for CD-TLR were compared between the CN and non-CN groups.
resultsThe incidence of CD-TLR was significantly higher in the CN group than in the non-CN group. In the landmark analysis at 1 year, the CN group showed a significantly higher incidence of CD-TLR within 1 year. However, the incidence of CD-TLR beyond 1 year was numerically lower in the CN group than in the non-CN group. In the multivariate Cox hazard model, CN was significantly associated with CD-TLR. In the CN group, in-stent CN was the major reason for CD-TLR (52%) and was observed mainly within 1 year (90%).
conclusionsIn the heavily calcified lesions requiring RA, CN was the factor associated with the higher rate of CD-TLR especially within 1 year. The timing of CD-TLR in lesions with CN may indicate that the process of CN protruding through the struts was progressed monthly.
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