Observational studyBMJ open2022
Troponin and short-term mortality in hospitalised patients with COVID-19 infection: a retrospective study in an inner-city London hospital.
Observational study in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 4 citations in OpenAlex.
- Increasing cardiac troponin-I level as a cardiac injury index correlates with in-hospital mortality and biofactors in severe hospitalised COVID-19 patients.Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy · 2023Article
- Normal high-sensitivity cardiac troponin for ruling-out inpatient mortality in acute COVID-19.PloS one · 2023Article
Corrections and comments
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Authors and funding
6 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the association between troponin positivity in patients hospitalised with COVID-19 and increased mortality in the short term.
settingHomerton University Hospital, an inner-city district general hospital in East London.
designA single-centre retrospective observational study.
participantsAll adults admitted with swab-proven RT-PCR COVID-19 to Homerton University Hospital from 4 February 2020 to 30 April 2020 (n=402). OUTCOME MEASURES: We analysed demographic and biochemical data collected from the patient record according to the primary outcome of death at 28 days during hospital admission.
methodsTroponin positivity was defined above the upper limit of normal according to our local laboratory assay (>15.5 ng/L for females, >34 ng/L for males). Univariate and multivariate logistical regression analyses were performed to evaluate the link between troponin positivity and death.
resultsMean age was 65.3 years for men compared with 63.8 years for women. A χ
conclusionsWe demonstrated an independent association between troponin positivity and increased short-term mortality in COVID-19 in a London district general hospital.
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