SynthesisEuropean respiratory review : an official journal of the European Respiratory Society2022
Does pulmonary rehabilitation address treatable traits? A systematic review.
Synthesis in European respiratory review : an official journal of the European Respiratory Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Combined Lifestyle Interventions in the Prevention and Management of Asthma and COPD: A Systematic Review.Nutrients · 2024Pooled it
- Exploring COPD Participants' Experiences in a Comprehensive Telewellness Program within a Mixed-Disability Cohort: A Qualitative Study.International journal of chronic obstructive pulmonary disease · 2026Article
- Low-cost pulmonary rehabilitation for chronic respiratory diseases: a narrative review.Frontiers in rehabilitation sciences · 2026Review
- Cough in pulmonary rehabilitation: a retrospective analysis of responders and nonresponders.ERJ open research · 2025Article
- Physical capacity and inactivity in obstructive airway diseases: a "can do, do do" analysis.ERJ open research · 2024Article
- Unravelling the complex interplay of factors behind exercise limitations and physical inactivity in COPD.Breathe (Sheffield, England) · 2024Review
- From treatable traits to GETomics in airway disease: moving towards clinical practice.European respiratory review : an official journal of the European Respiratory Society · 2024Review
- Pulmonary rehabilitation and physical interventions.European respiratory review : an official journal of the European Respiratory Society · 2023Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is growing interest in a "treatable traits" approach to pulmonary rehabilitation in chronic airways disease. The frequency with which pulmonary rehabilitation programmes address treatable traits is unknown.
methodsRandomised controlled trials of pulmonary rehabilitation compared to usual care in patients with stable chronic airways disease were included. The components of pulmonary rehabilitation delivered were extracted and mapped to treatable traits in pulmonary, extrapulmonary and behavioural/lifestyle domains. Meta-analysis was used to evaluate the impact of addressing >1 treatable trait on exercise capacity and health-related quality of life (HRQoL).
results116 trials were included (6893 participants). Almost all pulmonary rehabilitation programmes addressed deconditioning (97% of trials). The most commonly addressed extrapulmonary traits were nutritional status (obesity and cachexia, 18% each) and mood disturbance (anxiety and depression, 10% each). Behavioural/lifestyle traits most frequently addressed were nonadherence (46%), poor inhalation technique (24%) and poor family/social support (19%). Exercise capacity and HRQoL outcomes did not differ between studies that addressed deconditioning alone and those that targeted additional traits, but heterogeneity was high.
conclusionAside from deconditioning, treatable traits are infrequently addressed in existing trials of pulmonary rehabilitation. The potential of the treatable traits approach to improve pulmonary rehabilitation outcomes remains to be explored.
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Registered trials
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