Evidence map›Paper›PMID 36001985›Full record

ReviewPhysics in medicine and biology2022

The OpenGATE ecosystem for Monte Carlo simulation in medical physics.

David Sarrut, Nicolas Arbor, Thomas Baudier, Damian Borys, Ane Etxebeste, Hermann Fuchs, Jan Gajewski, Loïc Grevillot, Sébastien Jan, George C Kagadis and 11 more

Abstract readReview
In one paragraph

Review in Physics in medicine and biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Article
  2. In Vitro Radiobiological Evaluation of [Pharmaceuticals (Basel, Switzerland) · 2026
    Article
  3. Helium pencil beam commissioning and beam modeling.Physics and imaging in radiation oncology · 2026
    Article
  4. Article
  5. Time-of-Flight Requirements to Mitigate Blurring Induced by Annihilation Photon Acollinearity.IEEE transactions on radiation and plasma medical sciences · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Design and Evaluation of a Portable Pinhole SPECT System forDiagnostics (Basel, Switzerland) · 2025
    Article
  18. Article
  19. Article
  20. Dosimetry Software for Theranostic Applications: Current Capabilities and Future Prospects.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

David SarrutUniversité de Lyon; CREATIS; CNRS UMR5220; Inserm U1294; INSA-Lyon; Université Lyon 1, Léon Bérard cancer center, Lyon, France.ORCID 0000-0002-4854-4141
Nicolas ArborUniversité de Strasbourg, IPHC, CNRS, UMR7178, F-67037 Strasbourg, France.
Thomas BaudierUniversité de Lyon; CREATIS; CNRS UMR5220; Inserm U1294; INSA-Lyon; Université Lyon 1, Léon Bérard cancer center, Lyon, France.ORCID 0000-0001-9169-9627
Damian BorysDepartment of Systems Biology and Engineering, Silesian University of Technology, Gliwice, Poland.ORCID 0000-0003-0229-2601
Ane EtxebesteUniversité de Lyon; CREATIS; CNRS UMR5220; Inserm U1294; INSA-Lyon; Université Lyon 1, Léon Bérard cancer center, Lyon, France.ORCID 0000-0001-6280-9268
Hermann FuchsMedAustron Ion Therapy Center, Wiener Neustadt, Austria.ORCID 0000-0001-9003-5730
Jan GajewskiInstitute of Nuclear Physics Polish Academy of Sciences, Krakow, Poland.
Loïc GrevillotMedAustron Ion Therapy Center, Wiener Neustadt, Austria.
Sébastien JanUniversité Paris-Saclay, Inserm, CNRS, CEA, Laboratoire d'Imagerie Biomédicale Multimodale (BioMaps), F-91401 Orsay, France.
George C Kagadis3DMI Research Group, Department of Medical Physics, School of Medicine, University of Patras, Patras, Greece.ORCID 0000-0002-6983-2863
Han Gyu KangNational Institutes for Quantum Science and Technology (QST), 4-9-1 Anagawa, Inage-ku, Chiba 263-8555, Japan.ORCID 0000-0001-5338-4819
Assen KirovMemorial Sloan Kettering Cancer, New York, NY 10021, United States of America.
Olga KochebinaUniversité Paris-Saclay, Inserm, CNRS, CEA, Laboratoire d'Imagerie Biomédicale Multimodale (BioMaps), F-91401 Orsay, France.ORCID 0000-0003-4119-4465
Wojciech KrzemienHigh Energy Physics Division, National Centre for Nuclear Research, Otwock-Świerk, Poland.
Antony LomaxCenter for Proton Therapy, PSI, Switzerland.
Panagiotis PapadimitroulasBioemission Technology Solutions IKE, BIOEMTECH, Athens, Greece.ORCID 0000-0002-5981-6149
Christian PommranzWerner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tuebingen, Roentgenweg 13, D-72076 Tuebingen, Germany.ORCID 0000-0002-8640-6444
Emilie RoncaliUniversity of California Davis, Departments of Biomedical Engineering and Radiology, Davis, CA 95616, United States of America.ORCID 0000-0002-2439-1064
Antoni RucinskiInstitute of Nuclear Physics Polish Academy of Sciences, Krakow, Poland.ORCID 0000-0002-5815-4606
Carla WinterhalterCenter for Proton Therapy, PSI, Switzerland.
Lydia MaigneUniversité Clermont Auvergne, Laboratoire de Physique de Clermont, CNRS, UMR 6533, F-63178 Aubière, France.ORCID 0000-0002-0414-8462

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
New optical Monte Carlo simulation tools for nuclear medicineR01EB027130 · NIBIB · UNIVERSITY OF CALIFORNIA AT DAVIS · PI RONCALI, EMILIE · 2019 to 2023
$1.5M
Modeling of Light Transport in Nuclear Medicine Scintillation DetectorsR03EB020097 · NIBIB · UNIVERSITY OF CALIFORNIA AT DAVIS · PI RONCALI, EMILIE · 2015 to 2016
$157k
NCI NIH HHS P30 CA008748NIBIB NIH HHS R01 EB027130NIBIB NIH HHS R03 EB020097
6 · The paper itself

Abstract

This paper reviews the ecosystem of GATE, an open-source Monte Carlo toolkit for medical physics. Based on the shoulders of Geant4, the principal modules (geometry, physics, scorers) are described with brief descriptions of some key concepts (Volume, Actors, Digitizer). The main source code repositories are detailed together with the automated compilation and tests processes (Continuous Integration). We then described how the OpenGATE collaboration managed the collaborative development of about one hundred developers during almost 20 years. The impact of GATE on medical physics and cancer research is then summarized, and examples of a few key applications are given. Finally, future development perspectives are indicated.

Indexed as

EcosystemSoftwareComputer SimulationMonte Carlo MethodPhysicsGateGeant4Monte Carlosimulation

Identifiers

PMID36001985
PMCPMC11149651

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.