Evidence map›Paper›PMID 36001732›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Long noncoding RNA

Coen van Solingen, Yannick Cyr, Kaitlyn R Scacalossi, Maren de Vries, Tessa J Barrett, Annika de Jong, Morgane Gourvest, Tracy Zhang, Daniel Peled, Raadhika Kher and 8 more

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
4.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 47 citations in OpenAlex.

  1. Ebola virus exploits host lncRNAbioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Journal of virology · 2026
    Article
  7. Article
  8. Non-coding RNA · 2025
    Review
  9. The Multifaceted Roles ofNon-coding RNA · 2025
    Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. lncRNALife science alliance · 2025
    Article
  15. Review
  16. Getting the host antiviral machinery back on track: Targeting viral suppressors of RNA interference.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 2 institutions in 2 countries.

Coen van SolingenNYU Cardiovascular Research Center, Leon H. Charney Division of Cardiology, Department of Medicine, New York University Langone Health, New York, NY 10016.
Yannick CyrNYU Cardiovascular Research Center, Leon H. Charney Division of Cardiology, Department of Medicine, New York University Langone Health, New York, NY 10016.ORCID 0000-0002-0715-4112
Kaitlyn R ScacalossiNYU Cardiovascular Research Center, Leon H. Charney Division of Cardiology, Department of Medicine, New York University Langone Health, New York, NY 10016.
Maren de VriesDepartment of Microbiology, New York University Langone Health, New York, NY 10016.
Tessa J BarrettNYU Cardiovascular Research Center, Leon H. Charney Division of Cardiology, Department of Medicine, New York University Langone Health, New York, NY 10016.
Annika de JongNYU Cardiovascular Research Center, Leon H. Charney Division of Cardiology, Department of Medicine, New York University Langone Health, New York, NY 10016.
Morgane GourvestNYU Cardiovascular Research Center, Leon H. Charney Division of Cardiology, Department of Medicine, New York University Langone Health, New York, NY 10016.
Tracy ZhangNYU Cardiovascular Research Center, Leon H. Charney Division of Cardiology, Department of Medicine, New York University Langone Health, New York, NY 10016.
Daniel PeledNYU Cardiovascular Research Center, Leon H. Charney Division of Cardiology, Department of Medicine, New York University Langone Health, New York, NY 10016.
Raadhika KherNYU Cardiovascular Research Center, Leon H. Charney Division of Cardiology, Department of Medicine, New York University Langone Health, New York, NY 10016.
MacIntosh CornwellInstitute for Systems Genetics, Department of Medicine, New York University Langone Health, New York, NY 10016.ORCID 0000-0002-3041-4410
Michael A GildeaNYU Cardiovascular Research Center, Leon H. Charney Division of Cardiology, Department of Medicine, New York University Langone Health, New York, NY 10016.
Emily J BrownNYU Cardiovascular Research Center, Leon H. Charney Division of Cardiology, Department of Medicine, New York University Langone Health, New York, NY 10016.
Stephanie FanucchiLemba Therapeutics B.V., 6525 GA Nijmegen, The Netherlands.
Musa M MhlangaEpigenomics & Single Cell Biophysics Group, Department of Cell Biology FNWI, Radboud University, Nijmegen, 6500 HB, The Netherlands.ORCID 0000-0003-1381-3409
Jeffrey S BergerNYU Cardiovascular Research Center, Leon H. Charney Division of Cardiology, Department of Medicine, New York University Langone Health, New York, NY 10016.
Meike DittmannDepartment of Microbiology, New York University Langone Health, New York, NY 10016.
Kathryn J MooreNYU Cardiovascular Research Center, Leon H. Charney Division of Cardiology, Department of Medicine, New York University Langone Health, New York, NY 10016.ORCID 0000-0003-2505-2547
NYU Langone Health · USRadboud University Nijmegen · NL

Funding

ACTIV Integration of Host-targeting Therapies for COVID-19 Administrative Coordinating CenterOT2HL156812 · NHLBI · RESEARCH TRIANGLE INSTITUTE · PI NOLEN, TRACY L, THOMAS, SONIA M · 2020 to 2024
$1270.7M
Resolving Macrophage Inflammation in Atherosclerotic Plaques and Other Sites in Insulin ResistanceP01HL131481 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI KATHRYN J MOORE · 2017 to 2026
$27.3M
Non-coding RNA regulation of cholesterol homeostasis and atherosclerosisR35HL135799 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI MOORE, KATHRYN J · 2017 to 2023
$6.7M
Training Program in Cardiovascular SciencesT32HL098129 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Glenn I Fishman, Ira J Goldberg · 2009 to 2026
$5.9M
Mechanisms of Platelet Activity in Vascular DiseaseR35HL144993 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BERGER, JEFFREY S · 2019 to 2025
$5.5M
Platelet Activity and Vascular Health in Systemic Lupus ErythematosusR01HL139909 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BERGER, JEFFREY S, BUYON, JILL P · 2018 to 2022
$4.3M
ELF1 - Molecular mechanisms of a novel transcription factor with broad antiviral activityR01AI143639 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI WEISER, JEFFREY NEAL · 2019 to 2023
$2.5M
SERPINs as a novel family of innate antiviral molecules - Resubmission - 1R21AI139374 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI DITTMANN, MEIKE · 2019 to 2020
$466k
CIHR MFE-176524HHS | National Institutes of Health (NIH) R35HL13579NHLBI NIH HHS OT2 HL156812NHLBI NIH HHS P01 HL131481NHLBI NIH HHS R01 HL139909NHLBI NIH HHS R35 HL135799NHLBI NIH HHS R35 HL144993NHLBI NIH HHS T32 HL098129NIAID NIH HHS R01 AI143639NIAID NIH HHS R21 AI139374
6 · The paper itself

Abstract

Long noncoding RNAs (lncRNAs) have emerged as critical regulators of gene expression, yet their contribution to immune regulation in humans remains poorly understood. Here, we report that the primate-specific lncRNA

Indexed as

COVID-19DNA-Binding ProteinsImmunity, InnateInfluenza A virusInfluenza, HumanRNA, Long NoncodingSARS-CoV-2Transcription FactorsHumansInterferon Regulatory FactorsDNA-Binding ProteinsInterferon Regulatory FactorsIRF2BP2 protein, humanRNA, Long NoncodingTranscription Factorsantiviral responseinnate immune signalinginterferon-stimulated geneslncRNA

Identifiers

PMID36001732
PMCPMC9477407
OpenAlexW4293105353

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.