ArticleScience translational medicine2022
A genetically engineered
Open access · greenAbstract read
In one paragraph
Article in Science translational medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
8.8field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 46 citations in OpenAlex.
- Next-Generation Vaccines Against Neglected Diseases: New Promises from Genetically Modified Live-Attenuated Parasites and RNA Vaccines.Microorganisms · 2026Review
- The endemic dilemma: why whole sporozoite malaria vaccine efficacy falls in the field.Trends in parasitology · 2026Review
- From Yesterday to Tomorrow: How Vaccine Platforms Have Shaped the Vaccine and Treatment Evaluation Units.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025Article
- The path from early- to late-liver stage arresting genetically attenuated parasites as a malaria vaccination strategy.NPJ vaccines · 2025Review
- Malaria Vaccines: Current Achievements and Path Forward.Vaccines · 2025Review
- A Plasmodium LARC GAP provides preerythrocytic, stage and species transcending protection in mice.NPJ vaccines · 2025Article
- Systemic infection by Candida albicans requires FASN-α subunit induced cell wall remodeling to perturb immune response.PLoS pathogens · 2025Article
- Controlled human malaria infection studies: insights into recent advances and key immunological and ethical implementation lessons.Frontiers in immunology · 2025Review
- A conserved Plasmodium nuclear protein is critical for late liver stage development.Communications biology · 2024Article
- A Plasmodium late liver stage arresting GAP provides superior protection in mice.NPJ vaccines · 2024Article
- Experimental vaccination by single dose sporozoite injection of blood-stage attenuated malaria parasites.EMBO molecular medicine · 2024Article
- Vaccines and monoclonal antibodies: new tools for malaria control.Clinical microbiology reviews · 2024Review
- Statistical design and analysis of controlled human malaria infection trials.Malaria journal · 2024Article
- A replication competent Plasmodium falciparum parasite completely attenuated by dual gene deletion.EMBO molecular medicine · 2024Article
- Profiling the antibody response of humans protected by immunization with Plasmodium vivax radiation-attenuated sporozoites.Scientific reports · 2024Article
- Accelerated prime-and-trap vaccine regimen in mice using repRNA-based CSP malaria vaccine.NPJ vaccines · 2024Article
- CD8Frontiers in immunology · 2024Review
- Efficacy of aInfection and immunity · 2023Article
- Malaria Vaccines: Progress to Date.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2023Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
25 authors at 5 institutions in 1 country.
Sean C MurphyDepartment of Laboratory Medicine and Pathology and Center for Emerging and Re-emerging Infectious Diseases, University of Washington, Seattle, WA 98109, USA.ORCID 0000-0002-2048-0131
Ashley M VaughanCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109, USA.ORCID 0000-0001-5815-756X
James G KublinDepartment of Global Health, University of Washington, Seattle, WA 98195, USA.ORCID 0000-0003-1279-3741
Matthew FishbaugerCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109, USA.
Annette M SeilieDepartment of Laboratory Medicine and Pathology and Center for Emerging and Re-emerging Infectious Diseases, University of Washington, Seattle, WA 98109, USA.
Kurtis P CruzDepartment of Laboratory Medicine and Pathology and Center for Emerging and Re-emerging Infectious Diseases, University of Washington, Seattle, WA 98109, USA.
Tracie MankowskiCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109, USA.
Melike FiratCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109, USA.
Sara MageeCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109, USA.
Will BetzCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109, USA.ORCID 0000-0001-5709-2223
Heather KainCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109, USA.
Nelly CamargoCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109, USA.
Meseret T HaileCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109, USA.ORCID 0000-0002-5512-5260
Janna ArmstrongCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109, USA.ORCID 0000-0003-2719-9008
Emma FritzenCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109, USA.ORCID 0000-0002-1773-3070
Nina HertoghsCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109, USA.
Sudhir KumarCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109, USA.ORCID 0000-0002-2847-393X
D Noah SatherCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109, USA.ORCID 0000-0002-9128-172X
Leeya F PinderDepartment of Obstetrics and Gynecology, University of Washington, Seattle, WA 98195, USA.
Gregory A DeyeDivision of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health , Bethesda, MD, USA.ORCID 0000-0001-5527-4541
Shirley GalbiatiEmmes Company, Rockville, MD, USA.
Casey GeberEmmes Company, Rockville, MD, USA.
Jessica ButtsEmmes Company, Rockville, MD, USA.ORCID 0000-0002-3598-5861
Lisa A JacksonKaiser Permanente Washington Health Research Institute, Seattle, WA, USA.ORCID 0000-0002-1785-0218
Stefan H I KappeCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109, USA.ORCID 0000-0003-1540-1731
Infectious Disease Research Institute · USUniversity of Washington · USEmmes (United States) · USKaiser Permanente Washington Health Research Institute · USNational Institute of Allergy and Infectious Diseases · US
Funding
Kaiser Washington VTEU supplement 20-0003UM1AI148373 · NIAID · KAISER FOUNDATION RESEARCH INSTITUTE · PI LISA A JACKSON · 2020 to 2026
$24.4MNIAID NIH HHS HHSN272201300019CNIAID NIH HHS HHSN272201300019I
Abstract
Genetically engineered live
Indexed as
Insect Bites and StingsMalariaMalaria, FalciparumMalaria VaccinesParasitesAnimalsHumansPlasmodium falciparumSporozoitesVaccines, AttenuatedMalaria VaccinesVaccines, Attenuated
Identifiers
What OpenQuestion holds
Textmetadata
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Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.