ArticleScience advances2022
FIND-IT: Accelerated trait development for a green evolution.
Article in Science advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed.
- Point mutation in zinc sensor causes a threefold zinc level increase in Sorghum bicolor.The New phytologist · 2026Article
- Review
- Proteomic aging clocks in epidemiological studies: advances, applications and prospects.Nature aging · 2026Review
- Dormancy Versus Germination: 3D Protein Modeling and Evolutionary Analyses Define the Roles of Genetic Variants in the Barley MKK3 Enzyme.International journal of molecular sciences · 2026Article
- In silico prediction of variant effects: promises and limitations for precision plant breeding.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Review
- The putative endo-1,4-β-D-glucanase GLU3 regulates cellulose biosynthesis in barley roots.Plant physiology · 2025Article
- Sodium azide mutagenesis induces a unique pattern of mutations.PLoS genetics · 2025Article
- Metabolic engineering of narrow-leafed lupin for the production of enantiomerically pure (-)-sparteine.Plant biotechnology journal · 2025Article
- A barley pan-transcriptome reveals layers of genotype-dependent transcriptional complexity.Nature genetics · 2025Article
- Beyond the genome: the role of functional markers in contemporary plant breeding.Frontiers in plant science · 2025Review
- Article
- Just FIND-IT: Harnessing the true power of induced mutagenesis.Plant biotechnology journal · 2024Article
- Perspectives on improving photosynthesis to increase crop yield.The Plant cell · 2024Review
- A guide to barley mutants.Hereditas · 2024Review
- The potential for Scotch Malt Whisky flavour diversification by yeast.FEMS yeast research · 2024Review
- Editorial: Mutational breeding: from induced mutations to site-directed mutagenesis.Frontiers in plant science · 2024Article
- Optimized barley phytase gene expression by focused FIND-IT screening for mutations inFrontiers in plant science · 2024Article
- How CRISPR could yield the next blockbuster crop.Nature · 2024Article
- Adapting enzymes to improve their functionality in plants: why and how.Biochemical Society transactions · 2023Review
- HvSL1 and HvMADS16 promote stamen identity to restrict multiple ovary formation in barley.Journal of experimental botany · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
35 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Improved agricultural and industrial production organisms are required to meet the future global food demands and minimize the effects of climate change. A new resource for crop and microbe improvement, designated FIND-IT (Fast Identification of Nucleotide variants by droplet DigITal PCR), provides ultrafast identification and isolation of predetermined, targeted genetic variants in a screening cycle of less than 10 days. Using large-scale sample pooling in combination with droplet digital PCR (ddPCR) greatly increases the size of low-mutation density and screenable variant libraries and the probability of identifying the variant of interest. The method is validated by screening variant libraries totaling 500,000 barley (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.