ArticleLasers in medical science2022
Effect of low-level light therapy before radiotherapy in oral squamous cell carcinoma: An in vitro study.
Article in Lasers in medical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 11 citations in OpenAlex.
- Antimicrobial Photodynamic Therapy Associated With Systemic Treatment in Osteoradionecrosis: An In Vivo Study.Lasers in surgery and medicine · 2026Article
- Acupuncture to Improve Quality of Life in Patients with Head and Neck Cancer: A Randomized Clinical Trial.Cancers · 2026Article
- Photobiomodulation enhances radiosensitivity and suppresses oral squamous cell carcinoma in a 4NQO-induced mouse model.Lasers in medical science · 2025Article
- High-Energy Lasers in Oral Oncology: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2025Review
Corrections and comments
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Authors and funding
13 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Radiation therapy for head and neck squamous cell carcinoma (HNSCC) is associated with several complications. Although photobiomodulation (PBM) has radioprotective effects in normal tissue, it could also enhance the growth of neoplastic cells. Thus, the present study aimed to investigate the cellular response of oral squamous cell carcinoma with pre-exposure to low-level phototherapy before radiotherapy. SCC9, Cal-27, A431, and HaCaT cell lines were subjected to low-level light therapy and radiotherapy. The cells were treated with a single energy density (300 J/cm
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