Evidence map›Paper›PMID 36001075›Full record

ArticleEnvironmental science & technology2022

UV-C Light Completely Blocks Aerosol Transmission of Highly Contagious SARS-CoV-2 Variants WA1 and Delta in Hamsters.

Robert J Fischer, Julia R Port, Myndi G Holbrook, Kwe Claude Yinda, Martin Creusen, Jeroen Ter Stege, Marc de Samber, Vincent J Munster

Abstract read
In one paragraph

Article in Environmental science & technology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Non-pharmaceutical interventions for COVID-19: a systematic review on environmental control measures.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2023
    Pooled it
  2. Article
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  11. Impact of test methodology on the efficacy of triethylene glycol (Grignard Pure) against bacteriophage MS2.Aerosol science and technology : the journal of the American Association for Aerosol Research · 2023
    Article
  12. Article
  13. Article
  14. Towards Effective, Sustainable Solution for Hospital Wastewater Treatment to Cope with the Post-Pandemic Era.International journal of environmental research and public health · 2023
    Review
  15. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Robert J FischerLaboratory of Virology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana 59840 United States.ORCID 0000-0002-1816-472X
Julia R PortLaboratory of Virology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana 59840 United States.
Myndi G HolbrookLaboratory of Virology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana 59840 United States.
Kwe Claude YindaLaboratory of Virology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana 59840 United States.
Martin CreusenSignify, High Tech Campus 48, 5656 AE Eindhoven, The Netherlands.
Jeroen Ter StegeUVConsult BV, Hoofdstraat 249, 1611 AG Bovenkarspel, The Netherlands.
Marc de SamberSignify, High Tech Campus 48, 5656 AE Eindhoven, The Netherlands.
Vincent J MunsterLaboratory of Virology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana 59840 United States.

Funding

Virus Ecology UnitZIAAI001179 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI MUNSTER, VINCENT · 2013 to 2025
$24.3M
Intramural NIH HHS ZIA AI001179
6 · The paper itself

Abstract

Behavioral and medical control measures have not been effective in containing the spread of SARS-CoV-2 in large part due to the unwillingness of populations to adhere to "best practices". Ultraviolet light with wavelengths of between 200 and 280 nm (UV-C) and, in particular, germicidal ultraviolet light, which refers to wavelengths around 254 nm, have the potential to unobtrusively reduce the risk of SARS-CoV-2 transmission in enclosed spaces. We investigated the effectiveness of a strategy using UV-C light to prevent airborne transmission of the virus in a hamster model. Treatment of environmental air with 254 nm UV-C light prevented transmission of SARS-CoV-2 between individuals in a model using highly susceptible Syrian golden hamsters. The prevention of transmission of SARS-CoV-2 in a natural system by treating elements of the surrounding environment is one more weapon in the arsenal to combat COVID. The results presented indicate that coupling mitigation strategies utilizing UV-C light, along with current methods to reduce transmission risk, have the potential to allow a return to normal indoor activities.

Indexed as

COVID-19SARS-CoV-2AnimalsCricetinaeHumansRespiratory Aerosols and DropletsUltraviolet RaysaerosolCOVID19hamsterSARS-CoV-2transmissionUV-C

Identifiers

PMID36001075
PMCPMC9437662

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.