Evidence map›Paper›PMID 36000497›Full record

ArticleThe British journal of radiology2022

Implementation of a comprehensive set of optimised CBCT protocols and validation through imaging quality and dose audit.

Marina Khan, Navneet Sandhu, Marium Naeem, Rebecca Ealden, Michael Pearson, Abdirzak Ali, Ian Honey, Amanda Webster, David Eaton, Georgios Ntentas

Abstract read
In one paragraph

Article in The British journal of radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Marina KhanDepartment of Radiotherapy, Guy's & St Thomas' NHS Foundation Trust, London, UK.
Navneet SandhuDepartment of Medical Physics, Guy's & St Thomas' NHS Foundation Trust, London, UK.
Marium NaeemDepartment of Medical Physics, Guy's & St Thomas' NHS Foundation Trust, London, UK.
Rebecca EaldenDepartment of Medical Physics, Guy's & St Thomas' NHS Foundation Trust, London, UK.
Michael PearsonDepartment of Medical Physics, Guy's & St Thomas' NHS Foundation Trust, London, UK.
Abdirzak AliDepartment of Radiotherapy, Guy's & St Thomas' NHS Foundation Trust, London, UK.
Ian HoneyDepartment of Medical Physics, Guy's & St Thomas' NHS Foundation Trust, London, UK.
Amanda WebsterDepartment of Radiotherapy, University College Hospital, London, UK.
David EatonDepartment of Radiotherapy, Guy's & St Thomas' NHS Foundation Trust, London, UK.
Georgios NtentasDepartment of Radiotherapy, Guy's & St Thomas' NHS Foundation Trust, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesCone-beam computed tomography (CBCT) for radiotherapy treatment verification has increased in frequency; therefore, it is crucial to optimise image quality and radiation dose to patients. The aim of this study was to implement optimised CBCT protocols for the Varian TrueBeams for most tumour sites in adult patients.

methodsA combination of patient size-specific CBCT protocols from the literature and developed in-house was used. Scans taken before and after optimisation were compared by senior radiographers and physicists to evaluate how changes affected image quality and clinical usability for online image registration. The change in dose for each new CBCT protocol was compared to the Varian default. A clinical audit was performed following implementation to evaluate the changes in imaging dose for all patients receiving a CBCT during that period.

resultsTen CBCT protocols were introduced including head and neck and patient-size-specific thorax and pelvis/abdomen protocols. Scans from 102 patients with images before and after optimisation were assessed, none of the scans showed image quality changes compromising clinical usability and for some image quality was improved. Between November 2020 and June 2021, 1185 patients had CBCTs using the new protocols. The imaging dose was reduced for 52% of patients, remained the same for 37% and increased for 12%.

conclusionsThis study showed that substantial dose reductions and image quality improvements can be achieved with simple changes in the default settings of the Varian TrueBeam CBCT without affecting the radiographers' confidence in online image registration. ADVANCES IN KNOWLEDGE: This study represents a comprehensive assessment and optimisation of CBCT protocols for most sites, validated on a large cohort of patients.

Indexed as

Spiral Cone-Beam Computed TomographyCone-Beam Computed TomographyHeadHumansPelvisPhantoms, Imaging

Identifiers

PMID36000497
PMCPMC9793481

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.