Evidence map›Paper›PMID 36000465›Full record

ArticleBone & joint open2022

Kinematic alignment in total knee arthroplasty: a five-year prospective, multicentre, survivorship study.

Ton Tran, Peter McEwen, Yi Peng, Adrian Trivett, Robert Steele, William Donnelly, Gavin Clark

Open access · goldAbstract read
In one paragraph

Article in Bone & joint open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 25 citations in OpenAlex.

  1. Trial
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  4. External femoral rotation of 2 degrees is associated with the lowest stuffing rates around the femur in functionally aligned TKA.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Ton TranMonash Health, Melbourne, Victoria, Australia.ORCID 0000-0002-2424-3408
Peter McEwenMater Hospital Pimlico, Townsville, Queensland, Australia.ORCID 0000-0001-5499-9532
Yi PengSouth Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.
Adrian TrivettMonash Health, Melbourne, Victoria, Australia.
Robert SteeleMonash Health, Melbourne, Victoria, Australia.
William DonnellyAustralian Orthopaedic Association National Joint Replacement Registry, Adelaide, South Australia, Australia.
Gavin ClarkRoyal Perth Hospital, Perth, Western Australia, Australia.ORCID 0000-0003-3967-1613
Monash Health · AUAustralian Orthopaedic Association · AUMater Misericordiae Hospital · AUSouth Australian Health and Medical Research Institute · AUSt John of God Subiaco Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe mid-term results of kinematic alignment (KA) for total knee arthroplasty (TKA) using image derived instrumentation (IDI) have not been reported in detail, and questions remain regarding ligamentous stability and revisions. This paper aims to address the following: 1) what is the distribution of alignment of KA TKAs using IDI; 2) is a TKA alignment category associated with increased risk of failure or poor patient outcomes; 3) does extending limb alignment lead to changes in soft-tissue laxity; and 4) what is the five-year survivorship and outcomes of KA TKA using IDI?

methodsA prospective, multicentre, trial enrolled 100 patients undergoing KA TKA using IDI, with follow-up to five years. Alignment measures were conducted pre- and postoperatively to assess constitutional alignment and final implant position. Patient-reported outcome measures (PROMs) of pain and function were also included. The Australian Orthopaedic Association National Joint Arthroplasty Registry was used to assess survivorship.

resultsThe postoperative HKA distribution varied from 9° varus to 11° valgus. All PROMs showed statistical improvements at one year (p < 0.001), with further improvements at five years for Knee Osteoarthritis Outcome Score symptoms (p = 0.041) and Forgotten Joint Score (p = 0.011). Correlation analysis showed no difference (p = 0.610) between the hip-knee-ankle and joint line congruence angle at one and five years. Sub-group analysis showed no difference in PROMs for patients placed within 3° of neutral compared to those placed > 3°. There were no revisions for tibial loosening; however, there were reports of a higher incidence of poor patella tracking and patellofemoral stiffness.

conclusionPROMs were not impacted by postoperative alignment category. Ligamentous stability was maintained at five years with joint line obliquity. There were no revisions for tibial loosening despite a significant portion of tibiae placed in varus; however, KA executed with IDI resulted in a higher than anticipated rate of patella complications.Cite this article:

Indexed as

AlignmentArthroplastyForgotten Joint Score (FJS)hipjoint line obliquitiesKinematicKneeKnee Osteoarthritis Outcome ScoreKneespatellaPatient-reported outcome measures (PROMs)Replacementstiffnesstotal knee arthroplasty (TKA)valgus

Identifiers

PMID36000465
PMCPMC9422905
OpenAlexW4293171089

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.