ArticleJournal of the American Heart Association2022
Association of In-Hospital Hemoglobin Drop With Decreased Myocardial Salvage and Increased Long-Term Mortality in Patients With Acute ST-Segment-Elevation Myocardial Infarction.
Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Prognostic Value of the Osaka Prognostic Score for One-Year Mortality in Patients with ST-Segment Elevation Myocardial Infarction: A Retrospective Observational Cohort Study.Journal of clinical medicine · 2026Article
- Analyzing the effects of anemia on the outcomes of mechanical thrombectomy in ischemic stroke patients: a systematic review and meta-analysis.Annals of medicine and surgery (2012) · 2026Article
- Modeling of Factors Affecting Hospital Length of Stay in ST-Elevation Patients Using Logistic Regression Models: SEMI CI Study.Advanced biomedical research · 2026Article
- Sex-specific outcomes in myocardial infarction: a dual-cohort analysis using clinical and real-world data.Clinical research in cardiology : official journal of the German Cardiac Society · 2025Article
- Correlation Between Hemoglobin Levels and Severity of Coronary Artery Disease in Patients With Myocardial Infarction.Cureus · 2025Article
- Pre-percutaneous coronary intervention hemoglobin as a prognostic indicator for 6-month mortality in acute myocardial infarction patients: a secondary analysis of the Korea Acute Myocardial Infarction Registry National Institutes of Health cohort.Journal of thoracic disease · 2025Article
- Association between in-hospital hemoglobin drop without overt bleeding and 1-year outcome of percutaneous coronary intervention in acute myocardial infarction patients.Scientific reports · 2025Article
- Association between time-varying weighted hemoglobin and all-cause mortality in patients with acute myocardial infarction-related cardiogenic shock.Frontiers in cardiovascular medicine · 2025Article
- Association between haemoglobin decline and long-term outcomes in ST-elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention.The Journal of international medical research · 2024Article
- Association of hemoglobin drift and outcomes in patients with aneurysmal subarachnoid hemorrhage.Neurosurgical review · 2024Article
- Predicting left ventricular remodeling post-MI through coronary physiological measurements based on computational fluid dynamics.iScience · 2024Article
- Feasibility and safety values of activated clotting time-guided systemic heparinization in coil embolization for unruptured intracranial aneurysms.Acta neurochirurgica · 2023Article
- Hemoglobin to red cell distribution width ratio as a prognostic marker for ischemic stroke after mechanical thrombectomy.Frontiers in aging neuroscience · 2023Article
- Prediction models for major adverse cardiovascular events following ST-segment elevation myocardial infarction and subgroup-specific performance.Frontiers in cardiovascular medicine · 2023Article
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Authors and funding
13 authors.
Funding
Abstract
Background Anemia and blood loss occur often in patients with ST-segment-elevation myocardial infarction (STEMI). In-hospital hemoglobin drop is associated with 1-year mortality in patients with acute coronary syndrome. However, data on the effect of hemoglobin reduction on myocardial salvage and long-term outcomes are scarce. We investigated the impact of in-hospital hemoglobin drop on myocardial salvage and 5-year mortality in patients with STEMI treated with primary percutaneous coronary intervention. Methods and Results In-hospital hemoglobin drop was defined as a decrease in hemoglobin levels from admission and nadir hemoglobin values. Patients were categorized as having the following: no drop, minimal drop (<3 g/dL), minor drop (≥3 to <5 g/dL), and major drop (≥5 g/dL). Myocardial area at risk and infarct size were measured using serial single-photon emission computerized tomography imaging. The co-primary outcomes were myocardial salvage and 5-year all-cause mortality. Of 1204 patients, 1169 (97.1%) showed a hemoglobin drop during hospitalization: minimal, minor, and major drop occurred in 894 (74.3%), 214 (17.8%), and 61 (5.1%) patients, respectively. Myocardial salvage was reduced in patients with minimal (median, 0.53 [interquartile range, 0.27-0.83]), minor (median, 0.40 [interquartile range, 0.18-0.62]), and major (median, 0.40 [interquartile range, 0.14-0.77]) drop compared with patients without drop (median, 0.70 [interquartile range, 0.44-1.0],
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