Evidence map›Paper›PMID 36000259›Full record

ArticleJournal of psychopharmacology (Oxford, England)2023

Relationship between change in social evaluation learning and mood in early antidepressant treatment: A prospective cohort study in primary care.

Catherine Hobbs, Milly Beck, Faye Denham, Laura Pettitt, Julian Faraway, Marcus R Munafò, Jie Sui, David Kessler, Katherine S Button

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of psychopharmacology (Oxford, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Catherine HobbsDepartment of Psychology, University of Bath, Bath, UK.ORCID 0000-0002-2324-5882
Milly BeckDepartment of Psychology, University of Bath, Bath, UK.
Faye DenhamDepartment of Psychology, University of Bath, Bath, UK.
Laura PettittDepartment of Psychology, University of Bath, Bath, UK.
Julian FarawayDepartment of Mathematical Sciences, University of Bath, Bath, UK.
Marcus R MunafòSchool of Psychological Science, University of Bristol, Bristol, UK.
Jie SuiSchool of Psychology, University of Aberdeen, Aberdeen, UK.
David KesslerPopulation Health Sciences, University of Bristol, Bristol, UK.
Katherine S ButtonDepartment of Psychology, University of Bath, Bath, UK.
University of Bath · GBUniversity Hospitals Bristol NHS Foundation Trust · GBUniversity of Aberdeen · GBUniversity of Bristol · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAntidepressants are proposed to work by increasing sensitivity to positive versus negative information. Increasing positive affective learning within social contexts may help remediate negative self-schema. We investigated the association between change in biased learning of social evaluations about the self and others, and mood during early antidepressant treatment.

methodProspective cohort assessing patients recruited from primary care in South West England at four timepoints over the first 8 weeks of antidepressant treatment (

resultsWe did not find evidence that learning about the self was associated with a reduction in PHQ-9 (

conclusionsChange in social evaluation learning was associated with a reduction in anxiety but not depression. Antidepressants may treat anxiety symptoms by remediating negative affective biases towards socially threatening information directed towards the self and close others. However, our findings are based on exploratory analyses within a small sample without a control group and are therefore at risk of type 1 errors and order effects. Further research with larger samples is required.

Indexed as

AffectAntidepressive AgentsAnxietyHumansPrimary Health CareProspective StudiesAntidepressive AgentsantidepressantsDepressionemotional processingself-schemasocial cognition

Identifiers

PMID36000259
PMCPMC10076340
OpenAlexW4292869184

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.