ReviewJournal of enzyme inhibition and medicinal chemistry2022
Research progress on the synthesis and pharmacology of 1,3,4-oxadiazole and 1,2,4-oxadiazole derivatives: a mini review.
Review in Journal of enzyme inhibition and medicinal chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 81 citations in OpenAlex.
- Iodine-mediated 2,5-di(aryl/heteroaryl)-1,3,4-oxadiazoles: synthesis, andRSC advances · 2026Article
- Unlocking Anti-Toxoplasma Activity: The Essential Role of a Cis-Configured Vinyl Linker.Chemistry & biodiversity · 2026Article
- A new and efficient synthesis of substituted 2-amino-1,3,4-oxadiazoles from isothiocyanates and hydrazides.BMC chemistry · 2026Article
- Evaluation of the in vitro activity of synthetic derivatives of N-cyclohexyl-3-(3-methylphenyl)-1,2,4-oxadiazole-5-amine on the strain y of Trypanosoma cruzi and an in vivo toxicity study.Memorias do Instituto Oswaldo Cruz · 2026Article
- Design and pharmacological assessment of naproxen-ibuprofen linked NSAIDs as selective COX-2 modulators in inflammatory pathways.Inflammopharmacology · 2025Article
- Coumarin derivatives containing the 1,3,4 oxadiazole/thiadiazole moiety discovered as potential anti-tobacco mosaic virus agents.Molecular diversity · 2025Article
- Review
- Advances in Mechanochemical Methods for One-Pot Multistep Organic Synthesis.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Review
- Article
- Synthesis, Pharmacological Activities, Structure-activity Relationship of 1,3,4-Oxadiazole-Piperazine Conjugates: A Review.Medicinal chemistry (Shariqah (United Arab Emirates)) · 2025Review
- Discovery of FO-4-15, a novel 1,2,4-oxadiazole derivative, ameliorates cognitive impairments in 3×Tg mice by activating the mGluR1/CaMKIIα pathway.Acta pharmacologica Sinica · 2025Article
- Design, synthesis, and apoptotic antiproliferative action of new 1,2,3-triazole/1,2,4-oxadiazole hybrids as dual EGFR/VEGFR-2 inhibitors.Journal of enzyme inhibition and medicinal chemistry · 2024Article
- 1,3,4-Oxadiazole Scaffold in Antidiabetic Drug Discovery: An Overview.Mini reviews in medicinal chemistry · 2024Review
- A combined crystallographic and theoretical investigation of noncovalent interactions in 1,3,4-oxadiazole-2-thione-RSC advances · 2023Article
- Room Temperature Synthesis of Bioactive 1,2,4-Oxadiazoles.International journal of molecular sciences · 2023Review
- Evaluation of Antidiabetic Activity of Oxadiazole Derivative in Rats.Evidence-based complementary and alternative medicine : eCAM · 2023Article
- Identification of Novel Artemisinin Hybrids Induce Apoptosis and Ferroptosis in MCF-7 Cells.International journal of molecular sciences · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oxadiazole is a five-membered heterocyclic compound containing two nitrogen atoms and one oxygen atom. The 1,3,4-oxadiazole and 1,2,4-oxadiazole have favourable physical, chemical, and pharmacokinetic properties, which significantly increase their pharmacological activity
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.