Evidence map›Paper›PMID 36000168›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2022

Discovery of new 1

Ahmed A Gaber, Mohamed Sobhy, Abdallah Turky, Hanan Gaber Abdulwahab, Ahmed A Al-Karmalawy, Mostafa A Elhendawy, Mohamed M Radwan, Eslam B Elkaeed, Ibrahim M Ibrahim, Heba S A Elzahabi and 1 more

Abstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Crystal structure of 1-phenyl-1Acta crystallographica. Section E, Crystallographic communications · 2025
    Article
  6. Article
  7. Article
  8. Synthesis of New Pyrazolo[3,4-Molecules (Basel, Switzerland) · 2024
    Article
  9. Review
  10. Development of Novel Class of Phenylpyrazolo[3,4-International journal of molecular sciences · 2023
    Article
  11. Review
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ahmed A GaberDepartment of Pharmaceutical Organic Chemistry, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.
Mohamed SobhyDepartment of Pharmaceutical Organic Chemistry, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.
Abdallah TurkyDepartment of Pharmaceutical Organic Chemistry, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.
Hanan Gaber AbdulwahabDepartment of Pharmaceutical Medicinal Chemistry and Drug Design, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt.
Ahmed A Al-KarmalawyDepartment of Pharmaceutical Medicinal Chemistry, Faculty of Pharmacy, Horus University-Egypt, New Damietta, Egypt.ORCID 0000-0002-8173-6073
Mostafa A ElhendawyDepartment of Chemistry and Biochemistry, University of Mississippi, MS, USA.
Mohamed M RadwanNational Center for Natural Products Research, University of Mississippi, University, MS, USA.
Eslam B ElkaeedDepartment of Pharmaceutical Sciences, College of Pharmacy, AlMaarefa University, Riyadh, Saudi Arabia.
Ibrahim M IbrahimBiophysics Department, Faculty of Science, Cairo University, Cairo, Egypt.
Heba S A ElzahabiDepartment of Pharmaceutical Medicinal Chemistry and Drug Design, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt.
Ibrahim H EissaPharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.ORCID 0000-0002-6955-2263

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

New 1

Indexed as

Antineoplastic AgentsLung NeoplasmsCell Line, TumorCell ProliferationDrug Screening Assays, AntitumorErbB ReceptorsHumansMolecular Docking SimulationMolecular StructureMutationProtein Kinase InhibitorsPyrimidinesStructure-Activity RelationshipAntineoplastic AgentsEGFR protein, humanErbB ReceptorsProtein Kinase InhibitorsPyrimidines1H-pyrazolo[3,4-d]pyrimidineAnti-proliferativeapoptosisEGFR inhibitorsmolecular docking

Identifiers

PMID36000168
PMCPMC9466626

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.