ReviewCureus2022
Carpal Tunnel Syndrome: Pathophysiology and Comprehensive Guidelines for Clinical Evaluation and Treatment.
Review in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 36 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Hematological and Metabolic Markers in Carpal Tunnel Syndrome
Effects of Radial Pressure Wave Therapy Modulation in Patients With Carpal Tunnel Syndrome: A Double-Blind Randomized Clinical Trial.
Who cites it
36 citing papers in PubMed, 75 citations in OpenAlex.
- Influence of Demographic Factors on Presentation, Symptoms and Function in Carpal Tunnel Syndrome.Healthcare (Basel, Switzerland) · 2026Article
- Discordance Between Ultrasonographic and Clinical Outcomes After Corticosteroid Injection in Sjögren's Disease-Associated Carpal Tunnel Syndrome.International journal of molecular sciences · 2026Article
- Health-related factors and epigenetic alterations in metabolic comorbidities patients and smokers with carpal tunnel syndrome: a preliminary investigation of patient-derived samples.Journal of orthopaedic surgery and research · 2026Article
- Incidence of Carpal Tunnel Syndrome After the Diagnosis of Ulnar Neuropathy.Journal of hand surgery global online · 2026Article
- PubMed: an untapped source for open educational resource images.Journal of the Medical Library Association : JMLA · 2026Article
- Carpal tunnel syndrome caused by tophaceous gout: a case series and review of the literature.International journal of surgery case reports · 2026Article
- Immune cells mediated the causal relationship between gut microbiota and carpal tunnel syndrome: A Mendelian randomization study.Medicine · 2026Article
- Perineural Steroid Injections in Cubital Tunnel Syndrome: A Systematic Review and Meta-Analysis.Cureus · 2026Review
- Clinical Role of Corticosteroids Versus Platelet Rich Plasma Injections in the Management of Carpal Tunnel Syndrome: a Narrative Review.Current pain and headache reports · 2026Review
- Correlation Between Ultrasound and Nerve Conduction Study Findings in Evaluating Carpal Tunnel Syndrome.Cureus · 2026Article
- Evaluation of Clemastine's Effects on Clinical and Electrodiagnostic Parameters in Individuals With CTS: A Preliminary Placebo-Controlled Double-Blind RCT.Archives of rehabilitation research and clinical translation · 2025Article
- Utilization of a Deep Learning Algorithm for Automated Segmentation of Median Nerve from Ultrasound Obtained from the Distal Forearm and Wrist.Bioengineering (Basel, Switzerland) · 2025Article
- The Role of an Educational Program in Reducing Symptom Severity in Women with High Risk for Carpal Tunnel Syndrome.Medical sciences (Basel, Switzerland) · 2025Article
- Comparison of the establishment of a rabbit model of carpal tunnel syndrome under ultrasound-guided and landmark-guided methods.Scientific reports · 2025Article
- Distinct characteristics of carpal tunnel syndrome among Sjögren's disease patients and their clinical implications.Reumatologia · 2025Article
- Prevalence of hand paresthesia and numbness in painful shoulders: a narrative review.Annals of joint · 2025Review
- Article
- The Rising Popularity of Growth Hormone Therapy and Ensuing Orthopedic Complications in the Pediatric Population: A Review.Children (Basel, Switzerland) · 2024Review
- Prevalence and Risk Factors Associated With Carpal Tunnel Syndrome Among Sudanese Females: A Cross-Sectional Study.Cureus · 2024Article
- Morphometric indices and carpal tunnel syndrome: a radiological study in female patients.Orthopadie (Heidelberg, Germany) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In carpal tunnel syndrome (CTS), the median nerve is compressed at the level of the carpal tunnel in the wrist. This entrapment manifests as unpleasant symptoms, such as burning, tingling, or numbness in the palm that extends to the fingers. As the disease progresses, afflicted individuals also report decreased grip strength accompanied by hand weakness and restricted movement. The first half of this review elaborates on CTS pathology by providing readers with a comprehensive understanding of the etiology, relevant anatomy, and disease mechanism. CTS is considered the most common entrapment neuropathy, affecting around 3-6% of the adult population. Further, CTS prevalence has seen a dramatic increase in the last few decades paralleling the growth of everyday technology usage. Despite how common it is to have CTS, it can be quite challenging for physicians to make a definite diagnosis due to differentials that present with overlapping symptoms. Even more difficult can be deciding on a course of treatment that is the most effective and considerate of patient needs. Thus arises the need for clear clinical direction, and hence we end with a discussion around such guidelines that serve as a starting point toward effective diagnoses and patient treatment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.