ArticleLaryngoscope investigative otolaryngology2022
Clinical detection of "extremely low-risk" follicular thyroid carcinoma: A population-based study of 7304 patients.
Article in Laryngoscope investigative otolaryngology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 5 citations in OpenAlex.
- Detection of RAS p.Q61R by Immunohistochemistry in Practice: A Clinicopathologic Study of 217 Thyroid Nodules with Molecular Correlates.Endocrine pathology · 2024Article
- Prognosis and influencing factors of follicular thyroid cancer.Cancer medicine · 2024Article
- Clinical detection of "extremely low-risk" follicular thyroid carcinoma: A population-based study of 7304 patients.Laryngoscope investigative otolaryngology · 2022Article
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
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Abstract
Background: Previous studies have not been consistent in the risk of metastasis in follicular thyroid carcinoma (FTC). Therefore, we conducted a large population study to stratify the risk of distant metastasis in FTC patients using only clinical parameters. Methods: We extracted FTC patients from The Surveillance, Epidemiology, and End Results (SEER) database and divided them into training and validation cohorts. Results: The two cohorts consisted of 4913 and 2391 patients, respectively. We developed a nomogram and risk table based on a logistic regression model using algorithm-selected variables. Receiver Operating Characteristic (ROC) analyses showed high discriminatory power in the training and validation cohorts (Area under the curve [AUC] of 0.85 and 0.84, respectively). Extremely low, low, intermediate, and high-risk groups had 0.3%, 1%, 3.5%, and 16.7% risk of distant metastasis, respectively. Conclusions: Our risk scoring table can separates patients into four risk groups and efficiently detect patients with almost no risk of metastasis.
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