Electrical Shunting Prevents the Decline of Galvanotaxis After Monophasic Pulsed Microcurrent Stimulation in Human Dermal Fibroblasts.

Mikiko Uemura, Masaharu Sugimoto, Yoshiyuki Yoshikawa, Rieko Inoue

Open access · greenAbstract read

In one paragraph

Article in Eplasty, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.1field-weighted citation impact, top 57% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

A Case of a Pressure Injury Where Electrical Stimulation Led to Team Cohesion and Enhanced Healing.Cureus · 2025
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Mikiko UemuraKansai University of Welfare Sciences, Faculty of Health Science, Department of Rehabilitation, Osaka, Japan.

Masaharu SugimotoToyama Rehabilitation Medical Health and Welfare College, Toyama, Toyama.

Yoshiyuki YoshikawaNaragakuen University, Faculty of Heath Science, Department of Rehabilitation, Ikoma, Nara.

Rieko InoueDepartment of Rehabilitation, Yoshida Hospital, Kobe, Japan.

Kansai University of Welfare Sciences · JPNaragakuen University · JPNishida Hospital · JPToyama College · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Electrical stimulation (ES) therapy is recommended for healing pressure injuries. Monophasic pulsed microcurrent stimulation promotes the migration of human dermal fibroblasts (HDFs) to the cathode, and ES potentially accelerates pressure injury healing. A reverse current is generated after ES in the human body; however, the effects of the electrical shunt in preventing the reverse current from migrating are unclear. Therefore, this study aimed to investigate the effects of an electrical shunt on the migration of HDFs. Methods: In the shunt groups, HDFs were electrically stimulated (0, 200, 400, and 600 µA) for 8 hours, and an electrical shunt was used to remove the electricity after ES. HDFs were observed under time-lapse microscopy for 24 hours. The migration ratio toward the cathode was calculated for each dish. Results: The migration ratio was significantly higher in the 200- Conclusions: A post-ES electrical shunt is important in preventing a decline in the migration effect of ES.

Indexed as

chronic woundelectrotherapymicrocurrentphysical therapypressure ulcer

Identifiers

PMID36000005

PMCPMC9361395

OpenAlexW4293275428

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.