Evidence map›Paper›PMID 35999963›Full record

ArticleClinical kidney journal2022

COVID-19 infection and renal injury: where is the place for acute interstitial nephritis disease?

Juan León-Román, Irene Agraz, Ander Vergara, Natalia Ramos, Nestor Toapanta, Clara García-Carro, Alejandra Gabaldón, Roxana Bury, Sheila Bermejo, Oriol Bestard and 1 more

Abstract read
In one paragraph

Article in Clinical kidney journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Juan León-RománVall d'Hebron University Hospital, Department of Nephrology, Barcelona, Spain.
Irene AgrazVall d'Hebron University Hospital, Department of Nephrology, Barcelona, Spain.
Ander VergaraVall d'Hebron University Hospital, Department of Nephrology, Barcelona, Spain.
Natalia RamosVall d'Hebron University Hospital, Department of Nephrology, Barcelona, Spain.
Nestor ToapantaVall d'Hebron University Hospital, Department of Nephrology, Barcelona, Spain.ORCID https://orcid.org/0000-0001-5983-6863
Clara García-CarroClinico San Carlos University Hospital, Department of Nephrology, Madrid, Spain.ORCID https://orcid.org/0000-0002-5130-603X
Alejandra GabaldónVall d'Hebron University Hospital, Department of Pathology, Barcelona, Spain.
Roxana BuryVall d'Hebron University Hospital, Department of Nephrology, Barcelona, Spain.
Sheila BermejoVall d'Hebron University Hospital, Department of Nephrology, Barcelona, Spain.
Oriol BestardVall d'Hebron University Hospital, Department of Nephrology, Barcelona, Spain.
María José SolerVall d'Hebron University Hospital, Department of Nephrology, Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Novel coronavirus disease infection (coronavirus disease 2019, COVID-19) was declared a global pandemic in March 2020 and since then has become a major public health problem. The prevalence of COVID-19 infection and acute kidney injury (AKI) is variable depending on several factors such as race/ethnicity and severity of illness. The pathophysiology of renal involvement in COVID-19 infection is not entirely clear, but it could be in part explained by the viral tropism in the kidney parenchyma. AKI in COVID-19 infection can be either by direct invasion of the virus or as a consequence of immunologic response. Diverse studies have focused on the effect of COVID-19 on glomerulonephritis (GN) patients or the 'novo' GN; however, the effect of COVID-19 in acute tubulointerstitial nephritis (ATIN) has been scarcely studied. In this article, we present five cases with different spectrums of COVID-19 infection and ATIN that may suggest that recent diagnosis of ATIN is accompanied by a worse clinical prognosis in comparison with long-term diagnosed ATIN.

Indexed as

acute kidney injuryacute tubulointerstitial nephritisCOVID-19kidney biopsySARS-CoV-2

Identifiers

PMID35999963
PMCPMC8992323

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.