Evidence map›Paper›PMID 35999702›Full record

ArticleDrug delivery2022

A novel saponin liposomes based on the couplet medicines of

Chunjing Guo, Yanguo Su, Hui Wang, Min Cao, Ningning Diao, Zhongxin Liu, Daquan Chen, Ming Kong

Open access · goldAbstract read
In one paragraph

Article in Drug delivery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
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  5. Article
  6. Effect of Jiegeng () on Jingjie () "" into the lungs based on pharmacokinetics.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Chunjing GuoCollege of Marine Life Science, Ocean University of China, Qingdao266003, P.R. China.
Yanguo SuSchool of Pharmacy, Yantai University, Yantai264005, P.R. China.
Hui WangGynecology Department, Affiliated hospital of Weifang Medical University, Weifang261053, P.R. China.
Min CaoSchool of Pharmacy, Yantai University, Yantai264005, P.R. China.
Ningning DiaoSchool of Pharmacy, Yantai University, Yantai264005, P.R. China.
Zhongxin LiuSchool of Pharmacy, Yantai University, Yantai264005, P.R. China.
Daquan ChenSchool of Pharmacy, Yantai University, Yantai264005, P.R. China.ORCID 0000-0002-6796-0204
Ming KongCollege of Marine Life Science, Ocean University of China, Qingdao266003, P.R. China.
Yantai University · CNOcean University of China · CNWeifang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liposomes have been widely used for targeted drug delivery, but the disadvantages caused by cholesterol limit the application of conventional liposomes in cancer treatment. The compatibility basis of couplet medicines and the compatibility principle of the traditional Chinese medicine principle of 'monarch, minister, assistant and guide' are the important theoretical basis of Chinese medicine in the treatment of tumor and the important method to solve the problem of high toxicity. In this study, the active ingredients of the couplet medicines

Indexed as

Glycyrrhiza uralensisLung NeoplasmsPlatycodonSaponinsGlycyrrhizic AcidHumansLiposomesPlant RootsGlycyrrhizic AcidLiposomesSaponinsCouplet medicinesliposomesplatycodinsynergistic therapy

Identifiers

PMID35999702
PMCPMC9487977
OpenAlexW4292876650

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.