Variations of pulse pressure and central venous pressure may predict fluid responsiveness in mechanically ventilated patients during lung recruitment manoeuvre: an ancillary study.

Olivier Desebbe, Whitney Mondor, Laurent Gergele, Darren Raphael, Sylvain Vallier

Abstract read

In one paragraph

Article in BMC anesthesiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Central Venous Pressure as a Predictor of Acute Kidney Injury in Cardiac Surgery: A Systematic Review of Observational Studies.Diagnostics (Basel, Switzerland) · 2025
Review

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Olivier DesebbeDepartment of Anesthesiology and Intensive Care, Ramsay Sante Sauvegarde Clinic, Lyon, France. oldesebbe@yahoo.com.

Whitney MondorDepartment of Biosciences, Claude Bernard University, Lyon, France.

Laurent GergeleDepartment of Anesthesiology and Intensive Care, Ramsay Sante HPL Clinic, Saint-Etienne, France.

Darren RaphaelDepartment of Anesthesiology & Perioperative Care, University of California, Irvine, USA.

Sylvain VallierDepartment of Anesthesiology and Intensive Care, Elsan Alpes-Belledonne Clinic, Grenoble, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMaintaining a constant driving pressure during a prolonged sigh breath lung recruitment manoeuvre (LRM) from 20 to 45 cmH

methodsRetrospective analysis of a prospective study data set in 18 mechanically ventilated patients, in an intensive care unit. CVP, systemic arterial pressure parameters and stroke volume (SV) were recorded during prolonged LRM followed by a 500 mL crystalloid volume expansion. Patients were considered as fluid responders if SV increased more than 10%. Receiver-operating curves (ROC) analysis with the corresponding grey zone approach were performed.

resultsAreas under the ROC to predict fluid responsiveness for ΔCVP and ΔPP were not different between the successive stepwise increase of inspiratory pressures [0.88 and 0.89 for ΔCVP at 45 and 30 cm H

conclusionsA stepwise PEEP elevation recruitment manoeuvre of up to 30 cm H

Indexed as

Fluid TherapyRespiration, ArtificialBlood PressureCentral Venous PressureHemodynamicsHumansLungProspective StudiesRetrospective StudiesStroke VolumeCentral venous pressureFluid responsivenessLung recruitment manoeuvrePulse pressure

Identifiers

PMID35999508

DOI10.1186/s12871-022-01815-1

PMCPMC9396758

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.