Evidence map›Paper›PMID 35999474›Full record

ArticleEuropean journal of applied physiology2022

The effect of interval and continuous work on markers of acute kidney injury in a hot environment.

Jonathan Houck, Zachary McKenna, Zachary Fennel, Jeremy Ducharme, Andrew Wells, Christine Mermier, Michael Deyhle, Orlando Laitano, Jonathan Specht, Fabiano Amorim

Abstract read
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In one paragraph

Article in European journal of applied physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
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  9. Physical Exercise After Solid Organ Transplantation: A Cautionary Tale.Transplant international : official journal of the European Society for Organ Transplantation · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jonathan HouckDepartment of Health, Exercise and Sports Sciences, University of New Mexico, Albuquerque, NM, USA. houckj@husson.edu.ORCID http://orcid.org/0000-0002-5851-7526
Zachary McKennaDepartment of Health, Exercise and Sports Sciences, University of New Mexico, Albuquerque, NM, USA.
Zachary FennelDepartment of Health, Exercise and Sports Sciences, University of New Mexico, Albuquerque, NM, USA.
Jeremy DucharmeDepartment of Health, Exercise and Sports Sciences, University of New Mexico, Albuquerque, NM, USA.
Andrew WellsDepartment of Health, Exercise and Sports Sciences, University of New Mexico, Albuquerque, NM, USA.
Christine MermierDepartment of Health, Exercise and Sports Sciences, University of New Mexico, Albuquerque, NM, USA.
Michael DeyhleDepartment of Health, Exercise and Sports Sciences, University of New Mexico, Albuquerque, NM, USA.
Orlando LaitanoDepartment of Applied Physiology and Kinesiology, University of Florida, Gainesville, FL, USA.
Jonathan SpechtDepartment of Health, Exercise and Sports Sciences, University of New Mexico, Albuquerque, NM, USA.
Fabiano AmorimDepartment of Health, Exercise and Sports Sciences, University of New Mexico, Albuquerque, NM, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo examine the effect of high-intensity interval work (HIIW) and moderate-intensity continuous work (MICW) on markers of acute kidney injury (AKI) and kidney function in a hot environment.

methodsNine males completed 2 h of work (2 × 60 min with 10 min passive rest) in a hot environment (40 °C and 15% relative humidity) as either HIIW [2 min at 80% peak oxygen consumption (VO

resultsLog IGFBP7 (p < 0.01), log uNGAL (p < 0.01), and log uKIM-1 (p = 0.01) all displayed a main effect for time after both HIIW and MICW. IGFBP7 (p = 0.01) and uKIM-1 (p < 0.01), corrected for Uosm, were higher after HIIW compared to MICW at Post, while IGFBP7 was also higher 1 h Post after HIIW compared to MICW (p = 0.02). UFR significantly decreasing from Pre to Post (p < 0.01) and 1 h Post (p < 0.01), but no main effect for condition (p = 0.53).

conclusionBoth HIIW and MICW in a hot environment caused an increase in biomarkers of kidney injury (IGFBP7, KIM-1, and NGAL), but HIIW may have a greater impact on biomarkers related to AKI.

Indexed as

Acute Kidney InjuryLipocalinsBiomarkersCreatinineHumansInsulin-Like Growth Factor Binding ProteinsLipocalin-2MaleBiomarkersCreatinineInsulin-Like Growth Factor Binding ProteinsLipocalin-2LipocalinsAcute kidney injuryHeat stressHigh-intensity workKidney injury

Identifiers

PMID35999474

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.