Evidence map›Paper›PMID 35999424›Full record

ArticleMolecular imaging and biology2023

6-O-(2-[

Marjorie R Levinstein, Emilya N Ventriglia, Juan L Gomez, Reece C Budinich, János Marton, Gjermund Henriksen, Daniel P Holt, Robert F Dannals, Martin G Pomper, Carlos A Zarate and 2 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular imaging and biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Synthesis and In Silico Profile Modeling of 6-International journal of molecular sciences · 2025
    Article
  2. Review
  3. Exploring the role of mu opioid receptors in the therapeutic potential and abuse liability of (S)-ketamine.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Article
  4. Optimization of a Nucleophilic Two-Step Radiosynthesis of 6-International journal of molecular sciences · 2023
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 4 countries.

Marjorie R LevinsteinBiobehavioral Imaging and Molecular Neuropsychopharmacology Unit, National Institute On Drug Abuse Intramural Research Program, Baltimore, MD, 21224, USA.ORCID 0000-0003-4360-1503
Emilya N VentrigliaBiobehavioral Imaging and Molecular Neuropsychopharmacology Unit, National Institute On Drug Abuse Intramural Research Program, Baltimore, MD, 21224, USA.
Juan L GomezBiobehavioral Imaging and Molecular Neuropsychopharmacology Unit, National Institute On Drug Abuse Intramural Research Program, Baltimore, MD, 21224, USA.
Reece C BudinichBiobehavioral Imaging and Molecular Neuropsychopharmacology Unit, National Institute On Drug Abuse Intramural Research Program, Baltimore, MD, 21224, USA.
János MartonABX Advanced Biochemical Compounds Biomedizinische Forschungsreagenzien GmbH, Heinrich-Glaeser-Strasse 10-14, 01454, Radeberg, Germany.
Gjermund HenriksenInstitute of Basic Medical Sciences, University of Oslo, Blindern, P. O. Box 1105, N-0317, Oslo, Norway.
Daniel P HoltDepartment of Radiology, Johns Hopkins School of Medicine, Baltimore, MD, 21205, USA.
Robert F DannalsDepartment of Radiology, Johns Hopkins School of Medicine, Baltimore, MD, 21205, USA.
Martin G PomperDepartment of Radiology, Johns Hopkins School of Medicine, Baltimore, MD, 21205, USA.
Carlos A ZarateExperimental Therapeutics and Pathophysiology Branch, National Institute of Mental Health, Bethesda, MD, 20892, USA.
Jordi BonaventuraDepartament de Patologia I Terapèutica Experimental, Institut de Neurociències, Universitat de Barcelona, L'Hospitalet de Llobregat, Catalonia, Spain.ORCID 0000-0002-4745-0151
Michael MichaelidesBiobehavioral Imaging and Molecular Neuropsychopharmacology Unit, National Institute On Drug Abuse Intramural Research Program, Baltimore, MD, 21224, USA. mike.michaelides@nih.gov.ORCID 0000-0003-0398-4917
National Institute on Drug Abuse · USJohns Hopkins University · USABX-CRO Advanced Pharmaceutical Services (Germany) · DEInstitut d'Investigació Biomédica de Bellvitge · ESNational Institute of Mental Health · USUniversity of Oslo · NO

Funding

Biobehavioral Imaging and Molecular Neuropsychopharmacology of Substance Abuse MechanismsZIADA000069 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI MICHAELIDES, MICHAEL · 2016 to 2025
$18.9M
Training/Dissemination-Resource for Molecular Imaging Agents in Precision MedicineP41EB024495 · NIBIB · UT SOUTHWESTERN MEDICAL CENTER · PI MARTIN G POMPER · 2017 to 2026
$11.8M
Intramural NIH HHS ZIA DA000069MCIN/AEI /10.13039/501100011033 RYC-2019-027371-INIBIB NIH HHS P41 EB024495Spanish Ministerio de Sanidad 2021I070
6 · The paper itself

Abstract

purpose6-O-(2-[ PROCEDURE: Here, we report the first characterization of [

resultsWe also show that [

conclusionsTaken together with prior findings, our results suggest that [

Indexed as

Positron-Emission TomographyReceptors, Opioid, muAnimalsBrainDiprenorphineMiceRatsReceptors, OpioidDiprenorphineReceptors, OpioidReceptors, Opioid, muDiprenorphineIn vivoOpioidPET

Identifiers

PMID35999424
PMCPMC11882018
OpenAlexW4292846686

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.