Evidence map›Paper›PMID 35999274›Full record

ReviewBritish journal of cancer2022

Extruded small extracellular vesicles: splinters of circulating tumour cells may promote cancer metastasis?

Yuan Wan, Yi-Qiu Xia, Si-Yang Zheng

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in British journal of cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yuan Wan *The Pq Laboratory of BiomeDx/Rx, Department of Biomedical Engineering, Binghamton University, Binghamton, NY, 13902, USA. ywan@binghamton.edu.ORCID 0000-0002-0219-5118
Yi-Qiu Xia *Micro & Nano Integrated Biosystem Laboratory, Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA, 15213, USA.
Si-Yang ZhengMicro & Nano Integrated Biosystem Laboratory, Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA, 15213, USA. siyangz@andrew.cmu.edu.

Funding

Liquid biopsy of solitary pulmonary nodule with extracellular vesiclesR37CA255948 · NCI · STATE UNIVERSITY OF NY,BINGHAMTON · PI Yuan Wan · 2021 to 2026
$3.0M
Lipid nanoprobe integrated microdevice for extracellular vesicle isolation and duplex sequencing based mutation detection for non-invasive lung cancer diagnosisR01CA230339 · NCI · PENNSYLVANIA STATE UNIVERSITY, THE · PI ZHENG, SIYANG · 2018 to 2023
$1.9M
NCI NIH HHS R01 CA230339NCI NIH HHS R37 CA255948
6 · The paper itself

Abstract

We speculate ruptured circulating tumour cells (CTC) in capillaries could release a large number of small extracellular vesicle-like vesicles, namely mechanically extruded sEV (sEV

Indexed as

Extracellular VesiclesNeoplastic Cells, CirculatingDNAHumansMembrane ProteinsOncogenesDNAMembrane Proteins

Identifiers

PMID35999274
PMCPMC9519559

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.