Evidence map›Paper›PMID 35999227›Full record

ArticleNature communications2022

Nanoscale 3D spatial addressing and valence control of quantum dots using wireframe DNA origami.

Chi Chen, Xingfei Wei, Molly F Parsons, Jiajia Guo, James L Banal, Yinong Zhao, Madelyn N Scott, Gabriela S Schlau-Cohen, Rigoberto Hernandez, Mark Bathe

Abstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Structure and Zeta Potential of Gold Nanoparticles with Coronas of Varying Size and Composition.The journal of physical chemistry. C, Nanomaterials and interfaces · 2025
    Article
  8. Neuromorphic Computing Primitives Using Polymer-Networked Nanoparticles.The journal of physical chemistry. C, Nanomaterials and interfaces · 2024
    Article
  9. DNA-based nanostructures for RNA delivery.Medical review (2021) · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chi ChenDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.ORCID 0000-0002-6126-1824
Xingfei WeiDepartment of Chemistry, Johns Hopkins University, Baltimore, MD, 21218, USA.ORCID 0000-0001-5924-1579
Molly F ParsonsDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.ORCID 0000-0003-0370-8162
Jiajia GuoDepartment of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.ORCID 0000-0002-6118-8241
James L BanalDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Yinong ZhaoDepartment of Chemical & Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, 21218, USA.ORCID 0000-0002-7113-0481
Madelyn N ScottDepartment of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.ORCID 0000-0002-2232-2188
Gabriela S Schlau-CohenDepartment of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.ORCID 0000-0001-7746-2981
Rigoberto HernandezDepartment of Chemistry, Johns Hopkins University, Baltimore, MD, 21218, USA.ORCID 0000-0001-8526-7414
Mark BatheDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA. mark.bathe@mit.edu.ORCID 0000-0002-6199-6855

Funding

Nanometer distance assay to uncover protein dynamicsDP2GM128200 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI SCHLAU-COHEN, GABRIELA · 2017 to 2017
$2.4M
NIGMS NIH HHS DP2 GM128200
6 · The paper itself

Abstract

Control over the copy number and nanoscale positioning of quantum dots (QDs) is critical to their application to functional nanomaterials design. However, the multiple non-specific binding sites intrinsic to the surface of QDs have prevented their fabrication into multi-QD assemblies with programmed spatial positions. To overcome this challenge, we developed a general synthetic framework to selectively attach spatially addressable QDs on 3D wireframe DNA origami scaffolds using interfacial control of the QD surface. Using optical spectroscopy and molecular dynamics simulation, we investigated the fabrication of monovalent QDs of different sizes using chimeric single-stranded DNA to control QD surface chemistry. By understanding the relationship between chimeric single-stranded DNA length and QD size, we integrated single QDs into wireframe DNA origami objects and visualized the resulting QD-DNA assemblies using electron microscopy. Using these advances, we demonstrated the ability to program arbitrary 3D spatial relationships between QDs and dyes on DNA origami objects by fabricating energy-transfer circuits and colloidal molecules. Our design and fabrication approach enables the geometric control and spatial addressing of QDs together with the integration of other materials including dyes to fabricate hybrid materials for functional nanoscale photonic devices.

Indexed as

NanostructuresQuantum DotsColoring AgentsDNADNA, Single-StrandedColoring AgentsDNADNA, Single-Stranded

Identifiers

PMID35999227
PMCPMC9399249

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.