Evidence map›Paper›PMID 35999131›Full record

ReviewTrends in molecular medicine2022

Immunogenicity of SARS-CoV-2 vaccines in patients with cancer.

Helen Kakkassery, Esme Carpenter, Piers E M Patten, Sheeba Irshad

Open access · hybridAbstract readReview
In one paragraph

Review in Trends in molecular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Helen KakkasseryComprehensive Cancer Centre, School of Cancer & Pharmaceutical Sciences, King's College London, London, UK.
Esme CarpenterComprehensive Cancer Centre, School of Cancer & Pharmaceutical Sciences, King's College London, London, UK.
Piers E M PattenComprehensive Cancer Centre, School of Cancer & Pharmaceutical Sciences, King's College London, London, UK; Department of Haematological Medicine, King's College Hospital, London, UK.
Sheeba IrshadComprehensive Cancer Centre, School of Cancer & Pharmaceutical Sciences, King's College London, London, UK; Breast Cancer Now Research Unit, King's College London, London, UK; Guy's and St Thomas' NHS Foundation Trust, London, UK. Electronic address: sheeba.irshad@kcl.ac.uk.
King's College London · GB

Funding

Cancer Research UK 24869Medical Research Council MR/T005106/1
6 · The paper itself

Abstract

Transmission of the SARS-CoV-2 virus and its corresponding disease (COVID-19) has been shown to impose a higher burden on cancer patients than on the general population. Approved vaccines for use include new technology mRNA vaccines such as BNT162b2 (Pfizer-BioNTech) and mRNA-1273 (Moderna), and nonreplicating viral vector vaccines such as Ad26.COV2.S (Johnson & Johnson) and AZD1222 (AstraZeneca). Impaired or delayed humoral and diminished T-cell responses are evident in patients with cancer, especially in patients with haematological cancers or those under active chemotherapy. Herein we review the current data on vaccine immunogenicity in cancer patients, including recommendations for current practice and future research.

Indexed as

COVID-19NeoplasmsViral VaccinesAd26COVS1BNT162 VaccineChAdOx1 nCoV-19COVID-19 VaccinesHumansSARS-CoV-2Ad26COVS1BNT162 VaccineChAdOx1 nCoV-19COVID-19 VaccinesViral VaccinescancerCOVID-19haematological cancersSARS-CoV-2seroconversionvaccine immunogenicity

Identifiers

PMID35999131
PMCPMC9345889
OpenAlexW4289528744

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.