Evidence map›Paper›PMID 35998698›Full record

ArticleEnvironmental research2022

Contribution of gut bacteria to arsenic metabolism in the first year of life in a prospective birth cohort.

Hannah E Laue, Yuka Moroishi, Thomas J Palys, Brian P Jackson, Juliette C Madan, Margaret R Karagas

Open access · greenAbstract read
In one paragraph

Article in Environmental research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Hannah E LaueDepartment of Epidemiology, Geisel School of Medicine at Dartmouth, Hanover, NH, USA. Electronic address: Hannah.E.Laue@Dartmouth.edu.
Yuka MoroishiDepartment of Epidemiology, Geisel School of Medicine at Dartmouth, Hanover, NH, USA. Electronic address: Yuka.Moroishi.GR@Dartmouth.edu.
Thomas J PalysDepartment of Epidemiology, Geisel School of Medicine at Dartmouth, Hanover, NH, USA. Electronic address: Thomas.J.Palys@Dartmouth.edu.
Brian P JacksonDepartment of Earth Sciences, Dartmouth College, Hanover, NH, USA. Electronic address: Brian.P.Jackson@Dartmouth.edu.
Juliette C MadanDepartment of Epidemiology, Geisel School of Medicine at Dartmouth, Hanover, NH, USA; Department of Pediatrics and Psychiatry, Children's Hospital at Dartmouth,Lebanon, NH, United States. Electronic address: Juliette.C.Madan@Hitchcock.org.
Margaret R KaragasDepartment of Epidemiology, Geisel School of Medicine at Dartmouth, Hanover, NH, USA. Electronic address: Margaret.R.Karagas@Dartmouth.edu.
Dartmouth College · US

Funding

Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Fred W Kolling IV · 1985 to 2026
$91.3M
VARIATION IN BIOACCUMULATION AND BIOMAGNIFICATION OF METALS IN NORTHERN US LAKESP42ES007373 · NIEHS · DARTMOUTH COLLEGE · PI KARAGAS, MARGARET RITA · 1995 to 2019
$52.0M
A prospective study of critical environmental exposures in formative early life that impact lifelong health in rural US children: the New Hampshire Birth Cohort StudyUH3OD023275 · OD · DARTMOUTH COLLEGE · PI MARGARET Rita KARAGAS, Juliette Madan · 2018 to 2026
$44.3M
Relation Between In-utero Vitamin D and Immune Function in Early Childhood P20GM104416 · NIGMS · DARTMOUTH COLLEGE · PI SALAS DIAZ, LUCAS A · 2013 to 2022
$23.7M
Project 3: Placental Biomarkers of Exposure and Outcome (Marsit)P01ES022832 · NIEHS · DARTMOUTH COLLEGE · PI KARAGAS, MARGARET RITA · 2013 to 2018
$4.7M
Training Program for Quantitative Population Sciences in CancerT32CA134286 · NCI · DARTMOUTH COLLEGE · PI KARAGAS, MARGARET RITA, TOSTESON, TOR D · 2020 to 2024
$1.5M
Project 4: Determining How Arsenic Modulates Hedgehog Signaling During DevelopmenP20ES018175 · NIEHS · DARTMOUTH COLLEGE · PI KARAGAS, MARGARET RITA · 2010 to 2012
$892k
NCI NIH HHS P30 CA023108NCI NIH HHS T32 CA134286NIEHS NIH HHS P01 ES022832NIEHS NIH HHS P20 ES018175NIEHS NIH HHS P42 ES007373NIGMS NIH HHS P20 GM104416NIH HHS UH3 OD023275
6 · The paper itself

Abstract

Gut bacteria are at the interface of environmental exposures and their impact on human systems, and may alter host absorption, metabolism, and excretion of toxic chemicals. We investigated whether arsenic-metabolizing bacterial gene pathways related to urinary arsenic concentrations. In the New Hampshire Birth Cohort Study, urine and stool samples were obtained at six weeks (n = 186) and one year (n = 190) of age. Inorganic arsenic (iAs), monomethylarsonic acid (MMA), dimethylarsinic acid (DMA), and arsenobetaine (AsB) were quantified in infant urine samples using high-performance liquid chromatography with inductively coupled plasma mass spectrometry. Total arsenic exposure (tAs) was summarized as Σ(iAs, MMA, DMA) and log

Indexed as

ArsenicArsenicalsBacteriaBirth CohortCacodylic AcidChildCohort StudiesHumansProspective StudiesArsenicArsenicalsCacodylic AcidArsenicInfantMetagenomicsMicrobiome

Identifiers

PMID35998698
PMCPMC10319341
OpenAlexW4292730701

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.