Evidence map›Paper›PMID 35998303›Full record

Trial reportJournal of clinical oncology : official journal of the American Society of Clinical Oncology2022

Long-Term Efficacy and Safety of Luspatercept for Anemia Treatment in Patients With Lower-Risk Myelodysplastic Syndromes: The Phase II PACE-MDS Study.

Uwe Platzbecker, Katharina S Götze, Philipp Kiewe, Ulrich Germing, Karin Mayer, Markus Radsak, Thomas Wolff, Joerg Chromik, Katja Sockel, Uta Oelschlägel and 9 more

Open access · bronzeAbstract readClinical Trial, Phase II
In one paragraph

Trial report in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 13 institutions in 3 countries.

Uwe PlatzbeckerDepartment of Hematology, Cellular Therapy and Hemostaseology, Leipzig University Hospital, Leipzig, Germany.ORCID 0000-0003-1863-3239
Katharina S GötzeDepartment of Medicine III, Hematology and Medical Oncology, Technical University of Munich, Klinikum rechts der Isar, Munich, Germany.ORCID 0000-0002-6276-8002
Philipp KieweOnkologischer Schwerpunkt am Oskar-Helene-Heim, Berlin, Germany.
Ulrich GermingUniversitätsklinikum Düsseldorf, Düsseldorf, Germany.
Karin MayerDepartment of Internal Medicine III, University Hospital Bonn, Bonn, Germany.
Markus RadsakJohannes Gutenberg Universität Mainz, Mainz, Germany.ORCID 0000-0002-3991-5721
Thomas WolffOncoResearch Lerchenfeld UG, Hamburg, Germany.
Joerg ChromikUniversitätsklinikum Frankfurt, Goethe-Universität, Frankfurt/Main, Germany.
Katja SockelMedizinische Klinik und Poliklinik I, Universitätsklinikum Carl Gustav Carus, TU Dresden, Dresden, Germany.
Uta OelschlägelMedizinische Klinik und Poliklinik I, Universitätsklinikum Carl Gustav Carus, TU Dresden, Dresden, Germany.
Detlef HaaseDepartment of Hematology and Medical Oncology, University Medical Center Göttingen, Göttingen, Germany.
Thomas IllmerHematology Private Practice, Dresden, Germany.
Haifa Kathrin Al-AliDepartment of Hematology/Oncology, University Hospital Halle, Halle, Germany.
Gerda SillingDepartment of Hematology and Oncology, University of Aachen, Aachen, Germany.
Joseph G ReynoldsFormerly Acceleron Pharma, Inc, Cambridge, MA.
Xiaosha ZhangFormerly Acceleron Pharma, Inc, Cambridge, MA.
Kenneth M AttieFormerly Acceleron Pharma, Inc, Cambridge, MA.
Jeevan K ShettyCelgene International Sàrl, a Bristol-Myers Squibb Company, Boudry, Switzerland.
Aristoteles GiagounidisMarien Hospital Düsseldorf, Düsseldorf, Germany.ORCID 0000-0003-4083-4109
Acceleron Pharma (United States) · USKlinik und Poliklinik für Psychotherapie und Psychosomatik · DEBristol-Myers Squibb (Switzerland) · CHDüsseldorf University Hospital · DEGoethe University Frankfurt · DEJohannes Gutenberg University Mainz · DEMarien Hospital Düsseldorf · DEStiftung Oskar Helene Heim · DETUM Klinikum · DEUniversitätsmedizin Göttingen · DEUniversity Hospital Bonn · DEUniversity Hospital in Halle · DEUniversity Hospital Leipzig · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnemiaErythropoietinMyelodysplastic SyndromesActivin Receptors, Type IIHumansImmunoglobulin Fc FragmentsRecombinant Fusion ProteinsActivin Receptors, Type IIErythropoietinImmunoglobulin Fc FragmentsluspaterceptRecombinant Fusion Proteins

Identifiers

PMID35998303
PMCPMC9671752
OpenAlexW4292850114

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.