Observational studyJournal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology2022
Usefulness of implementing the OHIP-14 questionnaire to assess the impact of xerostomia and hyposalivation on quality of life in patients with primary Sjögren's syndrome.
Observational study in Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 29 citations in OpenAlex.
- Patient satisfaction and oral health-related quality of life for prefabricated teeth versus CAD-CAM milled acrylic resin denture teeth. A crossover clinical trial.BMC oral health · 2025Trial
- Prospective Sham-Controlled trial: acupuncture for symptom-relieving in patients with Sjögren's disease.Clinical rheumatology · 2025Trial
- Stimulated whole salivary flow is correlated with xerostomia severity and unstimulated whole salivary flow in adults with xerostomia taking anticholinergic medications.Archives of oral biology · 2026Article
- Oral health-related quality of life in Sjögren disease and non-Sjögren sicca: a cross-sectional study.Journal of patient-reported outcomes · 2026Article
- The Association Between Oral Diseases, Symptoms, and Oral Health-Related Quality of Life in 70-Year-Olds: A Cross-Sectional Study.Gerodontology · 2025Article
- Tooth Loss and Oral Health-Related Quality of Life: A Study in a Convenience Sample from Austria.Dentistry journal · 2025Article
- Evaluation of ultrasonographic features of major salivary glands and oral manifestations in patients with Sjögren's Syndrome.Medicina oral, patologia oral y cirugia bucal · 2025Article
- Clinical Features and Patient-Reported Outcomes in a Cohort of Patients with Sjögren's Disease.Journal of clinical medicine · 2025Article
- Oral Health-Related Quality of Life After Allogeneic Bone Marrow Transplant-A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2025Article
- AMY1 gene copy number associated with xerostomia and Sjögren's syndrome: a cross-sectional study.BMC oral health · 2025Article
- Evaluation of Polymethyl Methacrylate as a Provisional Material in a Fully Digital Workflow for Immediate-Load Complete-Arch Implant-Supported Prostheses over Three Months.Materials (Basel, Switzerland) · 2025Article
- Prognosis of Single Implant-Supported Prosthesis in Patients With Primary Sjögren's Syndrome: A Five-Year Prospective Clinical Study.Clinical oral implants research · 2025Article
- Evaluation of the Hypothalamic-Pituitary-Adrenal Axis in Patients with Primary Sjögren's Disease.Medicina (Kaunas, Lithuania) · 2024Article
- OHIP-14 Scores in Patients with Sjögren's Syndrome Compared to Sicca Syndrome: A Systematic Review with Meta-Analysis.International journal of dentistry · 2024Review
- Article
- The Translation, Validation and Cultural Adaptation of Questionnaires Assessing the Quality of Life and Fatigue among Patients with Sjogren's Syndrome for the Romanian Context.Clinics and practice · 2023Article
- Pain Assessment in Oral Medicine through Its Different Dimensions: A Comprehensive Review.Dentistry journal · 2023Review
- Usefulness of implementing the OHIP-14 questionnaire to assess the impact of xerostomia and hyposalivation on quality of life in patients with primary Sjögren's syndrome.Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology · 2022Observational
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this study is to analyze if the results of the Oral Health Impact Profile-14 questionnaire (OHIP-14) in patients with primary Sjögren's syndrome (pSS) are correlated with salivary flow and level of xerostomia.
methodsThis observational cross-sectional study was conducted in 61 patients (60 women, one man, mean age 57.64 [13.52]) diagnosed of pSS according to the American-European Criteria (2002). After recording demographic, medical and dental data (decayed-missing-filled teeth index [DMFT]), unstimulated (UWS) and stimulated (SWS) salivary flows were collected. Subsequently, UWS flow was categorized into two groups (<0.1 ml/min and ≥0.1 ml/min) and SWS into three groups (<0.1 ml/min, 0.1-0.7 ml/min and >0.7 ml/min). Patients also filled out a visual analog scale (VAS) for xerostomia and OHIP-14 for self-reported quality of life (QoL).
resultsData showed positive and significant correlation between OHIP-14 and xerostomia, based on VAS results (r = 0.52; p = 0.001). Furthermore, there was a negative correlation between UWS and OHIP-14 scores (r = -0.34; p = 0.006) and VAS for xerostomia (r = -0.22; p = 0.09). No significant correlation was found between SWS and OHIP-14 or VAS neither between DMFT and OHIP-14. When assessing the level of QoL by the UWS and SWS flow categories a significant association was found for UWS (p = 0.001) but not for SWS (p = 0.11). The OHIP-14 values were higher in the groups with lower salivary flow. The multiple linear regression to predict OHIP-14 only selected VAS for xerostomia as a statistically significant predictor.
conclusionsIncreased level of xerostomia and reduced UWS flow decrease oral health-related QoL in patients with pSS.
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