Evidence map›Paper›PMID 35997890›Full record

ArticleAnnals of nuclear medicine2022

Role of baseline

Tugba Akin Telli, Salih Ozguven, Ozkan Alan, Nuh Filizoglu, Mehmet Akif Ozturk, Nisanur Sariyar, Selver Isik, Rukiye Arikan, Nazim Can Demircan, Tugba Basoglu and 5 more

Abstract read
PubMed Publisher
In one paragraph

Article in Annals of nuclear medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Japanese journal of radiology · 2026
    Article
  2. Article
  3. Article
  4. Correlation of [European journal of nuclear medicine and molecular imaging · 2024
    Article
  5. Review
  6. Article
  7. From pixels to predictions: the scrying power of molecular imaging.European journal of nuclear medicine and molecular imaging · 2024
    Article
  8. Role of volumetric parameters obtained fromAnnals of nuclear medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Tugba Akin TelliDivision of Medical Oncology, School of Medicine, Marmara University, Istanbul, 34899, Turkey. tugbaakintelli@gmail.com.ORCID http://orcid.org/0000-0001-6535-6030
Salih OzguvenDepartment of Nuclear Medicine, School of Medicine, Marmara University, Istanbul, 34899, Turkey.
Ozkan AlanDivision of Medical Oncology, School of Medicine, Marmara University, Istanbul, 34899, Turkey.
Nuh FilizogluDepartment of Nuclear Medicine, School of Medicine, Marmara University, Istanbul, 34899, Turkey.
Mehmet Akif OzturkDivision of Medical Oncology, School of Medicine, Marmara University, Istanbul, 34899, Turkey.
Nisanur SariyarDepartment of Internal Medicine, School of Medicine, Marmara University, Istanbul, 34899, Turkey.
Selver IsikDivision of Medical Oncology, School of Medicine, Marmara University, Istanbul, 34899, Turkey.
Rukiye ArikanDivision of Medical Oncology, School of Medicine, Marmara University, Istanbul, 34899, Turkey.
Nazim Can DemircanDivision of Medical Oncology, School of Medicine, Marmara University, Istanbul, 34899, Turkey.
Tugba BasogluDivision of Medical Oncology, School of Medicine, Marmara University, Istanbul, 34899, Turkey.
Ilknur Alsan CetinDepartment of Radiation Oncology, School of Medicine, Marmara University, Istanbul, 34899, Turkey.
Tunc OnesDepartment of Nuclear Medicine, School of Medicine, Marmara University, Istanbul, 34899, Turkey.
Ozlem ErcelepDivision of Medical Oncology, School of Medicine, Marmara University, Istanbul, 34899, Turkey.
Faysal DaneDivision of Medical Oncology, School of Medicine, Marmara University, Istanbul, 34899, Turkey.
Perran Fulden YumukDivision of Medical Oncology, School of Medicine, Marmara University, Istanbul, 34899, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe aimed to evaluate whether baseline MATERIALS AND

methodsThis retrospective study included 54 mCRPC patients, who underwent baseline

resultsDocetaxel and abiraterone/enzalutamide were administered to 32 and 22 patients in the first-line setting, respectively. wbPSMA-TV (rho = 0.582, p = 0.004) and wbTL-PSMA (rho = 0.564, p = 0.007) showed moderate positive correlations with PSA levels. Older age (p = 0.02), higher wbPSMA-TV (p = 0.007), higher PSA (p = 0.01), higher number of bone metastases (p = 0.02), and lack of PSA response (p = 0.03) were significantly associated with an increased risk of mortality. Multivariate analysis determined wbPSMA-TV (HR: 1.003, 95% CI 1.001-1.004, p = 0.001) and PSA response (HR: 2.241, 95% CI 1.189-4.222, p = 0.01) as independent predictors of OS.

conclusionThe wbPSMA-TV may be a useful tool to reflect tumor burden and predict survival outcomes in patients with mCRPC.

Indexed as

Positron Emission Tomography Computed TomographyProstatic Neoplasms, Castration-ResistantDocetaxelGallium IsotopesGallium RadioisotopesHeterocyclic Compounds, 1-RingHumansMaleProstate-Specific AntigenRetrospective StudiesTreatment OutcomeDocetaxelgallium 68 PSMA-11Gallium IsotopesGallium RadioisotopesHeterocyclic Compounds, 1-RingProstate-Specific Antigen68Ga-PSMA PET/CTMetastatic castration-resistant prostate cancerSurvivalWhole-body volumetric parameters

Identifiers

PMID35997890

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.