ArticleBiomimetics (Basel, Switzerland)2022
A New Detergent for the Effective Decellularization of Bovine and Porcine Pericardia.
Article in Biomimetics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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Who cites it
9 citing papers in PubMed, 12 citations in OpenAlex.
- Article
- Extracellular Vesicles From Mesenchymal Stromal Cells Drive Muscle and Neuronal Regeneration Through TNFα Modulation.Journal of extracellular vesicles · 2026Article
- Systematic Review on Microtia: Current Knowledge and Future Directions.Children (Basel, Switzerland) · 2025Review
- Application of tergitol in liver decellularization and bioink preparation based on the obtained extracellular matrix.Frontiers in bioengineering and biotechnology · 2025Article
- Hybrid Materials for Vascular Applications: A Preliminary In Vitro Assessment.Bioengineering (Basel, Switzerland) · 2024Article
- Preliminary In Vitro Assessment of Decellularized Porcine Descending Aorta for Clinical Purposes.Journal of functional biomaterials · 2023Article
- Covalently Grafted Peptides to Decellularized Pericardium: Modulation of Surface Density.International journal of molecular sciences · 2023Article
- Performance of xenogeneic pulmonary visceral pleura as bioprosthetic heart valve cusps in swine.Frontiers in cardiovascular medicine · 2023Article
- Small intestinal submucosa-derived extracellular matrix as a heterotopic scaffold for cardiovascular applications.Frontiers in bioengineering and biotechnology · 2022Article
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 1 country.
Funding
Abstract
Human and animal pericardia are among the most widely exploited materials suitable to repair damaged tissues in the cardiovascular surgery context. Autologous, xenogeneic (chemically treated) and homologous pericardia are largely utilized, but they do exhibit some crucial drawbacks. Any tissue treated with glutaraldehyde is known to be prone to calcification in vivo, lacks regeneration potential, has limited durability, and can result in cytotoxicity. Moreover, autologous tissues have limited availability. Decellularized biological tissues represent a promising alternative: decellularization removes cellular and nuclear components from native tissues and makes them suitable for repopulation by autologous cells upon implantation into the body. The present work aims to assess the effects of a new detergent, i.e., Tergitol, for decellularizing bovine and porcine pericardia. The decellularization procedure successfully removed cells, while preserving the histoarchitecture of the extracellular matrix. No cytotoxic effect was observed. Therefore, decellularized pericardia showed potential to be used as scaffold for cardiovascular tissue regeneration.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.