Evidence map›Paper›PMID 35997385›Full record

ArticleClocks & sleep2022

NREM Parasomnias: Retrospective Analysis of Treatment Approaches and Comorbidities.

Naina Limbekar, Jonathan Pham, Rohit Budhiraja, Sogol Javaheri, Lawrence J Epstein, Salma Batool-Anwar, Milena Pavlova

Open access · goldAbstract read
In one paragraph

Article in Clocks & sleep, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Parasomnias in movement disorders: a narrative review.Journal of neural transmission (Vienna, Austria : 1996) · 2025
    Review
  4. Review
  5. Parasomnias in Pregnancy.Brain sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Naina LimbekarDivision of Sleep and Circadian Disorders, Brigham and Women's Faulkner Hospital, 1153 Centre Street, Boston, MA 02130, USA.
Jonathan PhamDivision of Sleep and Circadian Disorders, Brigham and Women's Faulkner Hospital, 1153 Centre Street, Boston, MA 02130, USA.
Rohit BudhirajaDivision of Sleep and Circadian Disorders, Brigham and Women's Faulkner Hospital, 1153 Centre Street, Boston, MA 02130, USA.
Sogol JavaheriDivision of Sleep and Circadian Disorders, Brigham and Women's Faulkner Hospital, 1153 Centre Street, Boston, MA 02130, USA.
Lawrence J EpsteinDivision of Sleep and Circadian Disorders, Brigham and Women's Faulkner Hospital, 1153 Centre Street, Boston, MA 02130, USA.
Salma Batool-AnwarDivision of Sleep and Circadian Disorders, Brigham and Women's Faulkner Hospital, 1153 Centre Street, Boston, MA 02130, USA.
Milena PavlovaDivision of Sleep and Circadian Disorders, Brigham and Women's Faulkner Hospital, 1153 Centre Street, Boston, MA 02130, USA.ORCID 0000-0001-7567-3099
Brigham and Women's Faulkner Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this retrospective analysis is to determine the most frequently prescribed medications for the treatment of NREM parasomnias and evaluate reported outcomes. We performed a retrospective chart review of all patients with NREM parasomnia diagnosed within Brigham and Women's Hospital (BWH) clinics examining the date of diagnosis, date of starting therapy, comorbidities, type of medication prescribed, and the reported change in symptoms or side effects at follow-up visits. From 2012 to 2019, 110 patients (59 females, 51 male) at BWH clinics received a diagnosis of NREM parasomnia, including sleepwalking and night terrors. The mean age was 44. Comorbidities included obstructive sleep apnea (OSA) (46%), periodic limb movement syndrome (PLMS) (13%), insomnia (19%), Restless leg syndrome (RLS) (9%), epilepsy (4%), and REM behavior disorder (RBD) (9%). Initial treatment strategies include behavioral and safety counseling only (34%), pharmacological treatment (29%), treatment of any comorbidity (28%), and combined treatment of any of the above (9%). Improvement was reported with: treatment of OSA (

Indexed as

benzodiazepinesconfusional arousalsmelatoninNREMobstructive sleep apneaparasomniassleep walkingtreatment

Identifiers

PMID35997385
PMCPMC9397000
OpenAlexW4292291606

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.