Evidence map›Paper›PMID 35997366›Full record

ArticleEmerging infectious diseases2022

Costs of Tuberculosis at 3 Treatment Centers, Canada, 2010-2016.

Jonathon R Campbell, Placide Nsengiyumva, Leslie Y Chiang, Frances Jamieson, Hadeel Khadawardi, Henry K-H Mah, Olivia Oxlade, Hayden Rasberry, Elizabeth Rea, Kamila Romanowski and 6 more

Open access · diamondAbstract read
In one paragraph

Article in Emerging infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Jonathon R Campbell
Placide Nsengiyumva
Leslie Y Chiang
Frances Jamieson
Hadeel Khadawardi
Henry K-H Mah
Olivia Oxlade
Hayden Rasberry
Elizabeth Rea
Kamila Romanowski
Natasha F Sabur
Beate Sander
Aashna Uppal
James C Johnston
Kevin Schwartzman
Sarah K Brode

Funding

CIHR PJT-153213
6 · The paper itself

Abstract

We estimated costs of managing different forms of tuberculosis (TB) across Canada by conducting a retrospective chart review and cost assessment of patients treated for TB infection, drug-susceptible TB (DS TB), isoniazid-resistant TB, or multidrug-resistant TB (MDR TB) at 3 treatment centers. We included 90 patients each with TB infection and DS TB, 71 with isoniazid-resistant TB, and 62 with MDR TB. Median per-patient costs for TB infection (in 2020 Canadian dollars) were $804 (interquartile range [IQR] $587-$1,205), for DS TB $12,148 (IQR $4,388-$24,842), for isoniazid-resistant TB $19,319 (IQR $7,117-$41,318), and for MDR TB $119,014 (IQR $80,642-$164,015). Compared with costs for managing DS TB, costs were 11.1 (95% CI 9.1-14.3) times lower for TB infection, 1.7 (95% CI 1.3-2.1) times higher for isoniazid-resistant TB, and 8.1 (95% CI 6.1-10.6) times higher for MDR TB. Broadened TB infection treatment could avert high costs associated with managing TB disease.

Indexed as

Latent TuberculosisMycobacterium tuberculosisTuberculosisTuberculosis, Multidrug-ResistantAntitubercular AgentsCanadaHumansIsoniazidRetrospective StudiesAntitubercular AgentsIsoniazidantimicrobial resistancebacteriabacterial infectionsCanadacost assessmentrespiratory infectionstuberculosis and other mycobacteria

Identifiers

PMID35997366
PMCPMC9423918
OpenAlexW4292680240

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.