Evidence map›Paper›PMID 35996930›Full record

Observational studyJournal of Korean medical science2022

Clinical Characteristics of Patients With Psoriatic Spondylitis Versus Those With Ankylosing Spondylitis: Features at Baseline Before Biologic Therapy.

Hyoun-Ah Kim, Eunyoung Lee, So Young Park, Shin-Seok Lee, Kichul Shin

Registry-linked trialOpen access · goldAbstract readObservational Study
In one paragraph

Observational study in Journal of Korean medical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01965132 (Korean College of Rheumatology Biologics and Targeted Therapy Registry), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01965132 recruitingnot on this map

Korean College of Rheumatology Biologics and Targeted Therapy Registry

Typeobservational_patient_registrySponsorSeoul National University HospitalRan2012 to 2030Enrolled10,000ConditionsRheumatoid Arthritis, Ankylosing Spondylitis, Psoriatic ArthritisArmsBiologic or targeted synthetic DMARD
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Hyoun-Ah KimDepartment of Rheumatology, Ajou University School of Medicine, Suwon, Korea.ORCID https://orcid.org/0000-0003-2609-3367
Eunyoung LeeOffice of Biostatistics, Medical Research Collaborating Center, Ajou Research Institute for Innovative Medicine, Ajou University Medical Center, Suwon, Korea.ORCID https://orcid.org/0000-0002-9440-9119
So Young ParkDivision of Rheumatology, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0001-7057-8244
Shin-Seok LeeDivision of Rheumatology, Department of Internal Medicine, Chonnam National University Medical School and Hospital, Gwangju, Korea.ORCID https://orcid.org/0000-0001-6810-7355
Kichul ShinDivision of Rheumatology, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0002-6749-7598
Ajou University · KRSeoul National University · KRChonnam National University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundClinical characteristics and manifestations of psoriatic arthritis (PsA) have been extensively studied in western countries, yet data of Korean patients with PsA are very limited. We aimed to investigate the clinical traits of patients with PsA and dissect the characteristics of those with axial involvement.

methodsIn this observational study, we analyzed clinical data of 109 patients with PsA who were enrolled in the Korean College of Rheumatology Biologics and Targeted Therapy registry between December 2012 and March 2022 at the time point of initiating or switching to a biologic agent. Data from 2,221 patients with ankylosing spondylitis (AS) registered during the same period were also analyzed. We divided patients with PsA into patients with or without axial involvement and then added AS patients with psoriasis (total three subgroups) for comparative analyses.

resultsAsymmetric oligoarthritis was the most common clinical manifestation in patients with PsA, followed by symmetric polyarthritis and spondylitis. Our analysis indicated that methotrexate and sulfasalazine were the two most prescribed disease-modifying antirheumatic drugs for patients with PsA before starting biologic therapy. The patients with psoriatic spondylitis had more peripheral joint involvement (

conclusionOur study shows that the degree of peripheral arthritis is less severe in Korean patients with PsA who require biologics and reestablishes that psoriatic spondylitis is a common and important clinical pattern in Korean patients with PsA.

trial registrationClinicalTrials.gov Identifier: NCT01965132.

Indexed as

Arthritis, PsoriaticBiological ProductsPsoriasisSpondylitisSpondylitis, AnkylosingBiological TherapyHLA-B27 AntigenHumansBiological ProductsHLA-B27 AntigenAnkylosing SpondylitisClinical CharacteristicsDisease-modifying Antirheumatic DrugHuman Leukocyte Antigen B27Psoriatic ArthritisPsoriatic Spondylitis

Identifiers

PMID35996930
PMCPMC9424747
OpenAlexW4290706633

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.