Evidence map›Paper›PMID 35996826›Full record

ArticleMolecules and cells2022

SF3B4 Depletion Retards the Growth of A549 Non-Small Cell Lung Cancer Cells via UBE4B-Mediated Regulation of p53/p21 and p27 Expression.

Hyungmin Kim, Jeehan Lee, Soon-Young Jung, Hye Hyeon Yun, Jeong-Heon Ko, Jeong-Hwa Lee

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules and cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Advances of E3 ligases in lung cancer.Biochemistry and biophysics reports · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Hyungmin KimDepartment of Biochemistry, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.ORCID https://orcid.org/0000-0002-1566-3953
Jeehan LeeDepartment of Biochemistry, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.ORCID https://orcid.org/0000-0002-6787-3565
Soon-Young JungDepartment of Biochemistry, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.ORCID https://orcid.org/0000-0003-2693-9377
Hye Hyeon YunDepartment of Biochemistry, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.ORCID https://orcid.org/0000-0003-0358-0269
Jeong-Heon KoGenome Editing Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Korea.ORCID https://orcid.org/0000-0003-3349-2534
Jeong-Hwa LeeDepartment of Biochemistry, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.ORCID https://orcid.org/0000-0002-5970-194X
Catholic University of Korea · KRKorea Research Institute of Bioscience and Biotechnology · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Splicing factor B subunit 4 (SF3B4), a component of the U2-pre-mRNA spliceosomal complex, contributes to tumorigenesis in several types of tumors. However, the oncogenic potential of SF3B4 in lung cancer has not yet been determined. The

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsCell Line, TumorCell ProliferationCyclin-Dependent Kinase Inhibitor p21HumansRNA PrecursorsRNA, Small InterferingRNA Splicing FactorsTumor Suppressor Protein p53Ubiquitin-Protein LigasesCyclin-Dependent Kinase Inhibitor p21RNA PrecursorsRNA, Small InterferingRNA Splicing FactorsSF3B4 protein, humanTumor Suppressor Protein p53UBE4B protein, humanUbiquitin-Protein Ligasesnon-small cell lung cancerp21p27p53SF3B4UBE4B

Identifiers

PMID35996826
PMCPMC9589371
OpenAlexW4292824052

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.