Evidence map›Paper›PMID 35996735›Full record

ArticleRadiology. Cardiothoracic imaging2022

Reduced Circumferential Strain in Athletes with Prior COVID-19.

Jean W Wassenaar, Daniel E Clark, Debra D Dixon, Kristen George-Durrett, Amar Parikh, Dan L Li, Michael T Baker, Deepak K Gupta, Sean G Hughes, Jonathan H Soslow and 1 more

Open access · greenAbstract read
In one paragraph

Article in Radiology. Cardiothoracic imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Radiology. Cardiothoracic imaging · 2023
    Review
  3. Multimodality Cardiac Imaging in COVID.Circulation research · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Jean W WassenaarVanderbilt University Medical Center, Division of Cardiovascular Medicine, Department of Internal Medicine, Nashville, TN, USA.ORCID https://orcid.org/0000-0002-2835-6338
Daniel E ClarkVanderbilt University Medical Center, Division of Cardiovascular Medicine, Department of Internal Medicine, Nashville, TN, USA.ORCID https://orcid.org/0000-0002-8054-0642
Debra D DixonVanderbilt University Medical Center, Division of Cardiovascular Medicine, Department of Internal Medicine, Nashville, TN, USA.ORCID https://orcid.org/0000-0003-1291-9447
Kristen George-DurrettMonroe Carell Jr. Children's Hospital at Vanderbilt, Thomas P. Graham Division of Pediatric Cardiology, Department of Pediatrics, Nashville, TN, USA.ORCID https://orcid.org/0000-0001-6009-5417
Amar ParikhVanderbilt University Medical Center, Division of Cardiovascular Medicine, Department of Internal Medicine, Nashville, TN, USA.
Dan L LiVanderbilt University Medical Center, Division of Cardiovascular Medicine, Department of Internal Medicine, Nashville, TN, USA.
Michael T BakerVanderbilt University Medical Center, Division of Cardiovascular Medicine, Department of Internal Medicine, Nashville, TN, USA.
Deepak K GuptaVanderbilt University Medical Center, Division of Cardiovascular Medicine, Department of Internal Medicine, Nashville, TN, USA.
Sean G HughesVanderbilt University Medical Center, Division of Cardiovascular Medicine, Department of Internal Medicine, Nashville, TN, USA.
Jonathan H Soslow *Monroe Carell Jr. Children's Hospital at Vanderbilt, Thomas P. Graham Division of Pediatric Cardiology, Department of Pediatrics, Nashville, TN, USA.ORCID https://orcid.org/0000-0001-9194-5330
Jeffrey M Dendy *Vanderbilt University Medical Center, Division of Cardiovascular Medicine, Department of Internal Medicine, Nashville, TN, USA.ORCID https://orcid.org/0000-0002-3490-9031
Vanderbilt University Medical Center · USMonroe Carell Jr. Children's Hospital · US

Funding

Vanderbilt Institute for Clinical and Translational Research (VICTR) -Identifying correlates of functional immunity in SARS-CoV-2 convalescent plasmaUL1TR002243 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Paul A. Harris, Wesley H Self · 2017 to 2026
$130.7M
Training In Cardiovascular ResearchT32HL007411 · NHLBI · VANDERBILT UNIVERSITY · PI BECKMAN, JOSHUA A · 1985 to 2020
$7.2M
NCATS NIH HHS UL1 TR002243NHLBI NIH HHS T32 HL007411
6 · The paper itself

Abstract

Purpose: To characterize global and segmental circumferential systolic strain (CS) measured by cardiac MRI in athletes after SARS-CoV-2 infection. Materials and Methods: This retrospective observational cohort study included 188 soldiers and collegiate athletes referred for cardiac MRI after SARS-CoV-2 infection (C19+) between July 2020 and February 2021 and a control group of 72 soldiers, collegiate, and high school athletes who underwent cardiac MRI from May 2019 to February 2020, prior to the first SARS-CoV-2 case detected in our region (C19-). Global and segmental CS were measured by feature tracking, then compared between each group using unadjusted and multivariable- adjusted models. Acute myocarditis was diagnosed according to the modified Lake Louise criteria and the location of pathologic late gadolinium enhancement (LGE) was ascertained. Results: Among the 188 C19+ athletes (median age, 25 years [IQR, 23-30]; 131 men), the majority had mild illness. Global CS significantly differed between C19+ and C19- groups, with a median of -24.0 (IQR -25.8, -21.4) versus. -25.0 (-28.0, -22.4), respectively (p = .009). This difference in CS persisted following adjustment for age, sex, body mass index, heart rate, and systolic blood pressure β coefficient 1.29 [95% CI: 0.20, 2.38], p = .02). In segmental analysis, the basal- and mid- inferoseptal, septal and inferolateral segments were significantly different (p < .05), which had a higher frequency of post-COVID late gadolinium enhancement. The global and segmental differences were similar after exclusion of athletes with myocarditis. Conclusion: Among athletes, SARS-CoV-2 infection was associated with a small but statistically significant reduced CS.

Identifiers

PMID35996735
PMCPMC9387168
OpenAlexW4290804238

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.