Evidence map›Paper›PMID 35996436›Full record

ArticleACS nanoscience Au2022

Photoresponsive Nanocarriers Based on Lithium Niobate Nanoparticles for Harmonic Imaging and On-Demand Release of Anticancer Chemotherapeutics.

Adrian Gheata, Geoffrey Gaulier, Gabriel Campargue, Jérémy Vuilleumier, Simon Kaiser, Ivan Gautschi, Florian Riporto, Sandrine Beauquis, Davide Staedler, Dario Diviani and 2 more

Open access · goldAbstract read
In one paragraph

Article in ACS nanoscience Au, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Adrian GheataInstitute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne, Group for Functionalized Biomaterials, EPFL SB ISIC SCI-SB-SG, Station 6, Lausanne CH-1015, Switzerland.
Geoffrey GaulierDepartment of Applied Physics, Université de Genève, 22 Chemin de Pinchat, Genève CH-1211, Switzerland.
Gabriel CampargueDepartment of Applied Physics, Université de Genève, 22 Chemin de Pinchat, Genève CH-1211, Switzerland.
Jérémy VuilleumierInstitute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne, Group for Functionalized Biomaterials, EPFL SB ISIC SCI-SB-SG, Station 6, Lausanne CH-1015, Switzerland.
Simon KaiserDepartment of Biomedical Sciences, Université de Lausanne, 7 Rue du Bugnon, Lausanne CH-1005, Switzerland.
Ivan GautschiDepartment of Biomedical Sciences, Université de Lausanne, 7 Rue du Bugnon, Lausanne CH-1005, Switzerland.
Florian RiportoSYMME, Université Savoie Mont-Blanc, Annecy F-74000, France.
Sandrine BeauquisSYMME, Université Savoie Mont-Blanc, Annecy F-74000, France.
Davide StaedlerDepartment of Biomedical Sciences, Université de Lausanne, 7 Rue du Bugnon, Lausanne CH-1005, Switzerland.
Dario DivianiDepartment of Biomedical Sciences, Université de Lausanne, 7 Rue du Bugnon, Lausanne CH-1005, Switzerland.
Luigi BonacinaDepartment of Applied Physics, Université de Genève, 22 Chemin de Pinchat, Genève CH-1211, Switzerland.ORCID https://orcid.org/0000-0003-0476-4473
Sandrine Gerber-LemaireInstitute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne, Group for Functionalized Biomaterials, EPFL SB ISIC SCI-SB-SG, Station 6, Lausanne CH-1015, Switzerland.ORCID https://orcid.org/0000-0002-6519-2782
University of Lausanne · CHÉcole Polytechnique Fédérale de Lausanne · CHUniversity of Geneva · CHUniversité Savoie Mont Blanc · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanoparticle-based drug delivery systems have the potential for increasing the efficiency of chemotherapeutics by enhancing the drug accumulation at specific target sites, thereby reducing adverse side effects and mitigating patient acquired resistance. In particular, photo-responsive nanomaterials have attracted much interest due to their ability to release molecular cargos on demand upon light irradiation. In some settings, they can also provide complementary information by optical imaging on the (sub)cellular scale. We herein present a system based on lithium niobate harmonic nanoparticles (LNO HNPs) for the decoupled multi-harmonic cell imaging and near-infrared light-triggered delivery of an erlotinib derivative (

Identifiers

PMID35996436
PMCPMC9389616
OpenAlexW4281701870

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.