ReviewMediators of inflammation2022
Impact of Periodontitis on Glycemic Control and Metabolic Status in Diabetes Patients: Current Knowledge on Early Disease Markers and Therapeutic Perspectives.
Review in Mediators of inflammation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 32 citations in OpenAlex.
- Association of Oral Health Assessment Tool Findings With Periodontal Screening Outcomes in Adults With Diabetes.Clinical and experimental dental research · 2026Article
- Gingival crevicular fluid levels of prolactin in periodontitis patients with controlled versus uncontrolled type 2 diabetes. a controlled clinical trial.Scientific reports · 2026Article
- Article
- GLP-1 Receptor Agonists in Periodontology: Mechanisms, Clinical Evidence, and Implications for Care.Biomolecules · 2026Review
- Improvements in Social Quality of Life for Recovering Addicts Receiving Dental Implant Rehabilitation.Cureus · 2026Article
- Histological analysis of periodontal tissues in patients with autoimmune diseases: a comparative cross-sectional study of inflammatory cell infiltration and epithelial barrier function.BMC oral health · 2026Article
- Exploring the Potential Mechanism of Smilax Glabra Roxb in Periodontitis Through Network Pharmacology and Molecular Docking.Current pharmaceutical design · 2026Article
- Integrating Periodontal Care Into Diabetes Management: A Narrative Perspective for Bangladesh With Global Relevance.Health science reports · 2025Article
- Blood glucose screening in dental clinics as an opportunity for detection of diabetes and prediabetes: The Kyoutou Dental and Diabetes (KDD) Study.Journal of diabetes investigation · 2025Article
- Examining gut microbiota and metabolites to clarify mechanisms ofWorld journal of diabetes · 2025Article
- Influencing Factors of Diabetic Patients of on Oral Health-Related Quality of Life: A Scoping Review.Iranian journal of public health · 2025Review
- An Artificial Intelligence-Based Fuzzy Logic System for Periodontitis Risk Assessment in Patients with Type 2 Diabetes Mellitus.Bioengineering (Basel, Switzerland) · 2025Article
- Modulatory role of exogenous arachidonic acid in periodontitis with type 2 diabetes mellitus mice.BMC oral health · 2025Article
- Dental and oral health assessments in the German National Cohort (NAKO).BMC oral health · 2025Article
- Effects of the Oral Health Promotion Program on oral health and oral microbiota changes in diabetic elderly individuals: a quasi-experimental study.BMC oral health · 2025Article
- Integrative Transcriptomic and Machine Learning Analysis Identifies Key Senescence-Associated Secretory Phenotype Genes Associated With Immune Dysregulation in Periodontitis.Human mutation · 2025Article
- Study on the Mechanism of the Leaves ofCombinatorial chemistry & high throughput screening · 2025Article
- Joint association between tobacco smoke exposure and periodontitis and glycemic status.Frontiers in endocrinology · 2025Article
- The Role of Autophagy in the Regulation of Bidirectional Relationships in Diabetic Periodontitis.Journal of inflammation research · 2025Review
- Prevalence and Severity of Periodontal Disease in Diabetic Patients in South Jordan: A Cross-Sectional Study.Cureus · 2024Article
Corrections and comments
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Authors and funding
8 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diabetes mellitus and periodontitis are two of the most common chronic diseases affecting the world's population, and they are intimately linked. For several years, in fact, it has been known that there is an interdependent relationship between the two diseases: Diabetes promotes the destruction of periodontal tissues, and periodontal disease negatively affects glycemic control. In relation to the control of dental plaque and oral dysbiosis responsible for periodontal disease, both nonsurgical and surgical therapy associated with proper home hygiene procedures have emerged as essential for good glycemic control. Moreover, several evidences suggest the essential role played by the control of periodontal disease in preventing the onset of the most common complications of diabetes: cardiovascular diseases, retinopathies, and other systemic diseases. The aim of this study is to update the current knowledge on the bi-univocal relationship between diabetes and periodontitis and the impact of therapy in the optimal management of these two disorders. From the information found in the literature, it has emerged that the correct treatment of periodontal disease in diabetic patients represents one of the main mechanisms and means currently established and valid to control periodontal disease and glucose metabolism and prevent the onset or development of diabetic complications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.