Evidence map›Paper›PMID 35996316›Full record

ArticleThe Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association2024

Simulation of Velopharyngeal Biomechanics Identifies Differences in Sphincter Pharyngoplasty Outcomes: A Matched Case-Control Study.

Thanh Tran, Jamie Perry, Silvia Blemker, Kazlin Mason

Abstract read
In one paragraph

Article in The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Diagnostic Utility of Velopharyngeal MRI in Children With Unexplained Velopharyngeal Insufficiency.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2026
    Article
  2. Levator Veli Palatini Muscle Ratio Is a Clinically Significant Anatomic Predictor for Velopharyngeal Surgical Need.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2025
    Observational
  3. Article
  4. Article
  5. Incorporating Velopharyngeal MRI into the Clinical Decision-Making Process for a Patient Presenting with Velopharyngeal Dysfunction Following a Failed Palatoplasty.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Thanh TranDepartment of Biomedical Engineering, University of Virginia, Charlottesville, VA, USA.
Jamie PerryDepartment of Communication Sciences & Disorders, East Carolina University, Greenville, NC, USA.ORCID 0000-0001-7866-9159
Silvia BlemkerDepartment of Biomedical Engineering, University of Virginia, Charlottesville, VA, USA.
Kazlin MasonDepartment of Human Services, University of Virginia, Charlottesville, VA, USA.ORCID 0000-0001-6839-9116

Funding

Institutional Career Development CoreKL2TR003016 · NCATS · UNIVERSITY OF VIRGINIA · PI PAPIN, JASON, WORRALL, BRADFORD B · 2019 to 2023
$3.9M
MRI-Based Modeling to Understand Anatomical Basis of Velopharyngeal DysfuntionR21DC014570 · NIDCD · UNIVERSITY OF VIRGINIA · PI BLEMKER, SILVIA SALINAS, PERRY, JAMIE L · 2015 to 2016
$409k
NCATS NIH HHS KL2 TR003016NIDCD NIH HHS R21 DC014570
6 · The paper itself

Abstract

The purpose of this study was to develop a framework for 3D subject-specific computational models capable of simulating velopharyngeal biomechanics for anatomic changes that occur following pharyngoplasty and to gain insight into biomechanical factors that may lead to different speech/surgical outcomes. Patient-specific models for two, matched participants with differing speech/surgical outcomes were developed: one with a successful pharyngoplasty outcome and one with a failed pharyngoplasty outcome. Surgical scenarios were simulated to model pharyngoplasty location, identify LVP muscle biomechanics, and identify an optimal pharyngoplasty location for each participant. These simulations illustrate the potential for optimizing pharyngoplasties based on patient-specific geometry.

Indexed as

Velopharyngeal InsufficiencyBiomechanical PhenomenaCase-Control StudiesComputer SimulationHumansPharynxTreatment Outcomemagnetic resonance imagingpharyngoplastyvelopharyngeal function

Identifiers

PMID35996316
PMCPMC9943793

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.