Evidence map›Paper›PMID 35996201›Full record

ArticleActa neuropathologica communications2022

BDNF-dependent modulation of axonal transport is selectively impaired in ALS.

Andrew P Tosolini, James N Sleigh, Sunaina Surana, Elena R Rhymes, Stephen D Cahalan, Giampietro Schiavo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta neuropathologica communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 55 citations in OpenAlex.

  1. Article
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  6. Disruption of BDNF signalling in neuropathologies.Biochemical Society transactions · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Andrew P TosoliniDepartment of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, London, WC1N 3BG, UK. a.tosolini@ucl.ac.uk.ORCID http://orcid.org/0000-0001-7651-7442
James N Sleigh *Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, London, WC1N 3BG, UK.ORCID http://orcid.org/0000-0002-3782-9045
Sunaina Surana *Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, London, WC1N 3BG, UK.ORCID http://orcid.org/0000-0002-7017-3105
Elena R RhymesDepartment of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, London, WC1N 3BG, UK.ORCID http://orcid.org/0000-0002-7103-5513
Stephen D CahalanComparative Neuromuscular Disease Laboratory, Department of Clinical Sciences and Services, Royal Veterinary College, University of London, London, NW1 0TU, UK.ORCID http://orcid.org/0000-0003-2287-1416
Giampietro SchiavoDepartment of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, London, WC1N 3BG, UK. giampietro.schiavo@ucl.ac.uk.ORCID http://orcid.org/0000-0002-4319-8745
UK Dementia Research Institute · GBNational Hospital for Neurology and Neurosurgery · GBUniversity of London · GBWellcome Centre for Human Neuroimaging · GB

Funding

Medical Research Council MR/S006990/1Wellcome Trust
6 · The paper itself

Abstract

Axonal transport ensures long-range delivery of essential cargoes between proximal and distal compartments, and is needed for neuronal development, function, and survival. Deficits in axonal transport have been detected at pre-symptomatic stages in the SOD1

Indexed as

Amyotrophic Lateral SclerosisAxonal TransportBrain-Derived Neurotrophic FactorAnimalsDisease Models, AnimalMiceMice, TransgenicMotor NeuronsSuperoxide Dismutase-1Bdnf protein, mouseBrain-Derived Neurotrophic FactorSuperoxide Dismutase-1Amyotrophic lateral sclerosisAxonal transportBDNFMotor neuronp75NTRTrkB

Identifiers

PMID35996201
PMCPMC9396851
OpenAlexW4292647774

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.