ArticleBMC geriatrics2022
Physical activity as a risk or protective factor for falls and fall-related fractures in non-frail and frail older adults: a longitudinal study.
Article in BMC geriatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 37 citations in OpenAlex.
- High-intensity interval swimming improves cardiovascular endurance, while aquatic resistance training enhances muscular strength in older adults.Scientific reports · 2024Trial
- Physical activity, health symptoms, and falls in older adults with different cognition levels: evidence from the Health and Retirement Study.BMC geriatrics · 2026Article
- Sedentary Lifestyle and Estimated Fracture Risk in the Elderly: A Cross-Sectional Study.Cureus · 2026Article
- Association Between the Serum Creatinine to Cystatin C Ratio, Physical Activity, and Frailty in Middle-Aged and Older Adults in China: A Nationwide Cohort Study.Life (Basel, Switzerland) · 2025Article
- Long Term Cardiovascular Safety of Testosterone Therapy: A Review of the TRAVERSE Study.The world journal of men's health · 2025Review
- Association between grip strength level and fall experience among older Chinese adults: a cross-sectional study from the CHARLS.BMC geriatrics · 2025Article
- Exploring predictors of the five-time sit-to-stand test based on cross-sectional findings from the Swedish National Study on Aging and Care (SNAC).BMC geriatrics · 2025Article
- Physical Activity Fragmentation and Falls in Older Adults: Findings From the National Health and Aging Trends Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- Effectiveness of Physical Activity Programs for Older Adults during COVID-19 across Districts with Different Healthcare Resource: A Case Study of Keelung City in Taiwan.Healthcare (Basel, Switzerland) · 2024Article
- The Association of Skeletal Muscle Energetics With Recurrent Falls in Older Adults Within the Study of Muscle, Mobility and Aging.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- Aging Hallmarks and Progression and Age-Related Diseases: A Landscape View of Research Advancement.ACS chemical neuroscience · 2024Review
- Associations among frailty status, hypertension, and fall risk in community-dwelling older adults.International journal of nursing sciences · 2024Article
- Effects of activities participation on frailty of older adults in China.Frontiers in public health · 2024Article
- Efficacy of extracting and preventively intervening late-stage older adults who are at high risk for spending high medical costs by using the health check-up system in Japan: a pilot study.Frontiers in public health · 2024Article
- Low physical activity and depression are the prominent predictive factors for falling in older adults: the Birjand Longitudinal Aging Study (BLAS).BMC geriatrics · 2023Article
- Development and validation of dynamic nomogram of frailty risk for older patients hospitalized with heart failure.International journal of nursing sciences · 2023Article
- The Role of Mitochondria in Mediation of Skeletal Muscle Repair.Muscles (Basel, Switzerland) · 2023Review
- Risk of ozone exposure-induced fracture.Frontiers in public health · 2023Article
- Multi-directional nature of falls among older adults: A rationale for prevention and management.Frontiers in public health · 2023Article
- Association of Frailty Status with Risk of Fall among Hospitalized Elderly Patients: A Cross-Sectional Study in an Acute Geriatric Unit.Medicines (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPhysical activity may be both a risk and protective factor for falls and fall-related fractures. Despite its positive effects on muscle and bone health, physical activity also increases exposure to situations where falls and fractures occur. This paradox could possibly be explained by frailty status. Therefore, the aim of this study was to investigate the associations between physical activity and both falls and fractures, and to determine whether frailty modifies the association of physical activity with falls, and fractures.
methodsData of 311 community-dwelling participants aged 75 years or older from the Longitudinal Aging Study Amsterdam, who participated in a three-year longitudinal study with five nine-monthly measurements between 2015/2016 and 2018/2019. Their mean age was 81.1 (SD 4.8) years and frailty was present in 30.9% of the participants. Physical activity in minutes per day was objectively assessed with an inertial sensor (Actigraph) for seven consecutive days. Falls and fractures were assessed every nine months using self-report during an interview over a follow-up period of three years. Frailty was determined at baseline using the frailty index. Associations were estimated using longitudinal logistic regression analyses based on generalized estimating equations.
resultsNo association between physical activity and falls was found (OR = 1.00, 95% CI: 0.99-1.00). Fall risk was higher in frail compared to non-frail adults (OR = 2.21, 95% CI: 1.33-3.68), but no effect modification was seen of frailty on the association between physical activity and falls. Also no relation between physical activity and fractures was found (OR = 1.00, 95% CI: 0.99-1.01). Fracture risk was higher in frail compared to non-frail adults (OR = 2.81, 95% CI: 1.02-7.75), but also no effect modification of frailty was present in the association between physical activity and fractures.
conclusionsNo association between physical activity and neither falls nor fractures was found, and frailty appeared not to be an effect modifier. However, frailty was a risk factor for falls and fractures in this population of older adults. Our findings suggest that physical activity can be safely recommended in non-frail and frail populations for general health benefits, without increasing the risk of falls.
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